今日摘要生成中
报告将于明天凌晨自动生成，明早九点准时推送
> @RuxandraTeslo: > This April, we got a drug revolutionary in 3 ways: daraxonrasib roughly doubles survival in metastatic pancreatic cancer, cracked RAS, a protein deemed untreatable for decades & pi
I input my IntellxxDNA genetics report as well as some recent blood work from TruAge TruDiagnostic and some bloodwork from Quest Diagnostics into Claude Cowork and some details of health interventions
> @demishassabis: > I’ve always believed the No.1 application of AI should be to improve human health. > > That work started with AlphaFold, and now at @IsomorphicLabs with the mission to reimagine d
Mounjaro beats Ozempic for weight loss. A head-to-head trial of 751 people proved it: 20.2% vs 13.7% at 72 weeks. And a triple-agonist in Phase 3 just hit 28.7%. But the weight loss isn't even the mo
> @demishassabis: > I’ve always believed the No.1 application of AI should be to improve human health. > > That work started with AlphaFold, and now at @IsomorphicLabs with the mission to reimagine d
> @JCellBiol: > #Eosinophils–usually linked to infection and disease–are actually helping to build the gut. New research from @PetrovaLab & @JBernierLatmani shows they reprogram fibroblasts into v
> @IsomorphicLabs: > Today marks a pivotal moment for Isomorphic Labs. We have secured $2.1 Billion in our second external funding round, led by Thrive Capital. They are joined at the table by Alphabe
🚨SURPASS-CVOT and major kidney events (Lancet), ATTAIN-MAINTAIN (Nature), and SURMOUNT-MAINTAIN (Lancet) are all out in publication TODAY. It’s a DELUGE. Currently processing….🤓
A 16-hour fasting regimen may boost cancer immunotherapy. Transient nutrient stress reshapes tumor metabolism, increasing isoleucine in the TME and enhancing CD8+ T cell function. In mice & patients,
At the 2026 @ARVOinfo conference, BioAge's Yan Wang, PhD (SVP, Translational Aging) and Aiden Eblimit, PhD (Principal Scientist) presented their poster entitled “Oral NLRP3 inhibition prevents age-dep
S-acylation of TDP43 regulates its condensation in amyotrophic lateral sclerosis: Molecular Cell https://t.co/LsV7gFlLIr
🧬 #BehindtheStudy: Dr. Stefanie Morgan joins Dr. Robert Dudley @agelessrx_ to discuss a #research paper she co-authored in Volume 17, Issue 4, titled “Influence of rapamycin on safety and healthspan
Had fun discussing AI innovations in health care with @TheAtlantic @tgoetz, highlighting work by @kenlkehl @ecerami @DFCIPopSci on AI for clinical trial matching in oncology + other exciting applicat
> @MaartenDik: > $VKTX Viking Therapeutics Presents Data from its 13-Week Phase 2 VENTURE-Oral Dosing Trial of VK2735 at European Congress on Obesity (ECO) 2026 > > Oral VK2735 demonstrated early, pr
𝐀𝐒𝐆𝐂𝐓 𝟐𝟎𝟐𝟔: @EpicrisprBio is already in the clinic with its epigenetic approach to genetic medicine. At ASGCT, it showed off how versatile this platform might be. #ASGCT2026 Full video: htt
Abu Dhabi opens a real-world test lab for longevity
NAD+ webinar set to examine delivery dilemma
The next step? Human safety trials. Read the full story on how researchers are closing in on this deadly virus: https://t.co/7lNYSSqnhk
𝐀𝐒𝐆𝐂𝐓 𝟐𝟎𝟐𝟔: @arbortx presented in vivo data today showing that they can deliver their RT editor to the CNS with a single AAV capsid. #ASGCT2026 Full video: https://t.co/zEbBmfbrTl https://t.
Had to repost this paper that the FDA knew and even published a report that patients with lung cancer who failed all standards of care die early because of lymphopenia. When T cell and NK cell count i
> @untillabs: > We’re putting the “reversible” in Reversible Cryopreservation 🧡 > > Our latest post breaks down how our rewarming process works and shares new human organ-scale rewarming data we’re
Without this kind of trial design, we might have been too slow to identify a treatment that saved ~1M lives globally from severe COVID. In March 2020, RECOVERY launched in the UK as a platform trial,
Longevity-linked APOE2 gene variant helps neurons repair DNA and resist aging Research from the Buck Institute reveals that the protective APOE2 variant, already associated with exceptional longevity
The West looks at Japan and sees clean streets and punctual trains. Japan looks at itself and sees a 2050 society where humans are free from the limits of body, brain, space, and time. This is liter
Forever Healthy Releases AI4L 1.0 for Practical Longevity
Preservation of mitochondrial membrane potential is necessary for lifespan extension from dietary restriction https://t.co/iBjKczAsbl
> @ycombinator: > FinalDose is building the first programmable drug platform - a single smart drug molecule that finds diseased cells by their DNA and destroys them. They're starting with all cancers.
> @moreisdifferent: > Since 2022 the Japanese have had access to Xocova, a once-daily SARS-CoV-2 antiviral that is superior to Paxlovid. It is even approved for prophylactic use in Japan. A critical u
This is it. Everything learned spending millions on longevity. From: Your Immortal Unc and Auntie. To: Our Immortal nieces and nephews. 0. Sleep is the world's most powerful drug. 1
Selective Elimination of TP53 Mutant Cells by Transcript-Activated Chromatin Shredding Read this great preprint by the Doudna lab now instead of posting about it in 1-2 yrs when its published in Natu
> @CellCellPress: > Now online! Galvanin (TMEM154) is an electric-field sensor for directed cell migration https://t.co/HuQNUNgiYd 🤯🤯🤯🤯
if you are alive in 2035 you are gonna be alive in 2100
> @matthewherper: > Marty Makary was the worst FDA commissioner in 25 years. Full stop. > > I have covered the FDA for that long, and I don’t say this lightly. He was, largely, an agent of chaos beca
🧠 AI Reveals MRI Signatures of Brain Aging and Neurodegeneration A new study by Nikhil N. Chaudhari and colleagues used interpretable deep learning to identify MRI patterns linked to brain aging and
Did you know there is a 95% chance you’re carrying the Epstein-Barr virus (EBV)? For most, it stays dormant. But for others, it’s linked to serious diseases like MS, lupus and even certain cancers.
> @AndrewE_Dunn: > NEW: Isomorphic Labs has $2.1 billion, one of the largest-ever raises for a privately-held biotech. > > I have 5 questions to watch going forward, in my latest for @endpts: https:
His claim is correct. We have a fertility crisis. > 62% sperm count drop globally 1973 - 2018 > 23% drop in just 16 years > rate of decline accelerating > dropping 2.64% per year since 2000 I expl
It was fitting that BAIO, in our very first newsletter, covered the breakthrough that ultimately paved the way for Isomorphic’s $2.1B raise. If you want to stay on top of the AI × bio revolution, make
🎧 Listen to our #pressrelease on the #research paper, "Host immunosenescence compromises Mycobacterium tuberculosis clearance." https://t.co/Gb8cxultPv #aging #audio #podcast #SoundCloud #PaperSpot
The Largest Small Molecule: Manufacturing Process for Entlicitide https://t.co/IbVfh1E3ny Thursday, June 4th, 2026 8 AM PT | 11 AM ET | 5 PM CET Atherosclerotic cardiovascular disease remains a leadi
"Come and help Merck to its former greatness and rightful place in history." Thursday, on ep. 3 of @approvedfm: the inside story of Keytruda, the best-selling cancer drug of all time. Feat. Roy Bayne
Green Gold: Tomatidine Reverses Cognitive Decline by Mending the Leaky Brain https://t.co/FUZLG4KPNf https://t.co/qBXhfCCrXL
> @phillipburks: > @RonDeSantis @iliketeslas We just passed 10k miles of FSD usage. It’s so much better than human drivers. https://t.co/m0c6qgrPgL Plus lower insurance rates when driving exclusively
The year of the vaginal microbiome is HERE. Have been waiting for this conversation to open up, thanks @ejdickson @WIRED for including me. https://t.co/cNLljqT0uw
> @Convokebio: > Today we're publishing our index of unmet needs in human disease: 2443 indications scored and ranked on burden of disease, prevalence, pipeline activity, and treatment burden. We hope
> @bryan_johnson: > This is it. > Everything learned spending millions on longevity. > > From: Your Immortal Unc and Auntie. > To: Our Immortal nieces and nephews. > > 0. Sleep is t
Clene gets FDA nod for ALS accelerated path
Med News: New blood tests on the market claim to screen for more than 50 types of #cancer. But how useful are these multicancer early detection tests? https://t.co/PFOlDngGsZ
Source: https://t.co/mCbId0mNGg
The microbiome of centenarians looks less like modern dysbiosis — and more like ecological balance. In this week’s Research Review, Dr. Makenna Lenover Moyer explores what extreme longevity reveals a
@elonmusk Go a step further: encourage users to 'program' themselves by curating their 'Following' tab and using that as their primary source of information gathering. AND THEN make sure users un
Vascular aging: A central driver of multimorbidity - "Proposes the “Vascular Senescence Hub” hypothesis, where vasculature actively drives systemic aging rather than being a passive victim." - "Eval
11. SGLT-2 inhibitors may represent pharmacological fasting—engaging the same longevity pathways as CR without sustained dietary deprivation. The question now is whether the magnitude of effect is su
How an ‘Impossible’ Idea Led to a Pancreatic Cancer Breakthrough An experimental drug, daraxonrasib, is the first to substantially extend the lives of patients with pancreatic cancer in a clinical tr
> @GStolyarovII: > Workshop: Seizing Policy Opportunities for Life Extension and Overcoming Political Obstacles in 2026 - https://t.co/oE4fHUULkf > > On Thursday, May 14, 2026, at the Vitalist Bay co
Trump says it’s an “honor” to have “Elon, Tim Apple, Larry Fink” and others joining him on the trip to China, where he says he’ll be “asking President Xi, a Leader of extraordinary distinction, to ‘op
Don’t reach for the bug spray: scientists find insects may feel pain after crickets nurse sore antennae
🔆 #PaperSpotlight: This #research paper was #published in Volume 18, titled "Host immunosenescence compromises Mycobacterium tuberculosis clearance." #PressRelease ⬇️ https://t.co/x26dqb92AI #agin
> @Cell_Metabolism: > Exerkine GPLD1 bridges liver and brain https://t.co/3yoyzJO4my https://t.co/PHQEu2zcKg Fortean Times strikes again
This discovery could be a gamechanger for hundreds of thousands of transplant patients and those with compromised immune systems who are most at risk from EBV reactivation.
Sources and caveats (all links go to the actual papers): Weight loss head-to-head: SURMOUNT-5: Tirzepatide vs semaglutide, NEJM May 2025 https://t.co/ZVBRwnVwji (Tirzepatide 20.2% vs semaglutide 13.7
$QURE up, @DrMakaryFDA down. Patients spoke. Scientists spoke. Congress started watching. And now the system moves. For #Huntington’s, rare diseases, and every community told to “wait”, a new chapter
> @Megatron_ron: > BREAKING: > > 🇮🇷 Iranian parliament will consider to make a Nuclear bomb > > If the US attacks us again, we will enrich uranium to the level of a nuclear bomb - Ebrahim Rezaei,
> @ValerieAnne1970: > THEY ARE KILLING OUR PETS — AND IT COULD BE SPREADING TO YOU! > > The USDA quietly approved Nobivac NXT — America’s first self-amplifying RNA vaccine for dogs and cats (rabies,
𝐀𝐒𝐆𝐂𝐓 𝟐𝟎𝟐𝟔: @AscidianTx is presenting initial human safety data from its RNA exon editing platform in a Stargardt disease trial. Full video: https://t.co/tDwUVIBbyV https://t.co/2cnJ8j6PVe
Last year I nearly shut down Blueprint. My reasoning was that in the grand game of existence, getting our societal goals right is the only thing that matters. In the long arc of time, it wouldn't mat
> @jfais20: > $XBI - $BMY following $GSK into massive collaboration with Hengrui Pharma... > > "Some analyses suggest China = a third of all pipeline projects worldwide!" > > Major changes needed a
> @femalelongevity: > PCOS officially has a new name as of today: PMOS (polyendocrine metabolic ovarian syndrome). > Published in The Lancet after an 11-year global consensus. Re-naming medical condi
> @WallStSai: > $XBI Top 10 Largest Global Pharma M&A Deals in 2026 > > What will be the next biggest deal ? > > $LLY $GILD $MRK $BIIB $NVS $PFE $BMY $NVS $MDGL $VKTX $RVMD https://t.co/VgyqsHz6
The biggest challenge in gene therapy may not be the therapy itself. It’s delivery: getting the right biology to the right cells safely and precisely. @nanogenomics https://t.co/LYWcgZMBrW
𝐀𝐒𝐆𝐂𝐓 𝟐𝟎𝟐𝟔: Genetic Medicines Expert @NucleaseLab highlights what are the key topics heading into the start of ASGCT. #ASGCT2026 Full video: https://t.co/Wvz1AKgauk https://t.co/rxbEQFNPE7
> @jrkelly: > It is telling that the 2nd largest private biotech financing in history is going to a biotech that outsources all their lab work. We need to have our “TSMC moment” for scientific lab wo
If aging isn't inevitable for a naked mole-rat, it doesn't have to be for humans either. We share 93% of our DNA. Biology has already solved the problem. Now it's up to us. That's all.
And here's @matthewherper on why Marty Makary was the worst FDA commissioner in 25 years https://t.co/a44yjB5sZn
🔆 #PaperSpotlight: A new #research paper was #published on May 4, titled “Host immunosenescence compromises Mycobacterium tuberculosis clearance.” @ICGEB 🔗 https://t.co/PpBsG7yH2v #aging #quote #
Crocetin Delays Brain and Body Aging by Increasing Cellular Energy Levels in Aged C57BL/6J Mice https://t.co/nTMkcOb1Vz
Can a #cancer patient fast for one week? It should increase efficacy of #immunotherapy Cell paper https://t.co/C6m8Y6dG5m
In this episode of Live Foreverish, Dr. Mike and Dr. Crystal sit down with Lauren Levy, a registered dietitian and expert in renal nutrition, to discuss how to slow the progression of chronic kidney d
Transcytosis-mediated anterograde transport of the receptor TrkA mediates the formation of presynaptic sites in sympathetic neurons | Science Signaling https://t.co/JlK9HHBqNr
How HIV-1 Develops Resistance to Broadly Neutralizing Antibodies Researchers mapped more than 100 mutations that allow diverse HIV-1 strains to evade broadly neutralizing antibodies @PaulBieniasz @R
🩸 Tiny brain bleeds may signal a brain that is aging faster than expected. In a new neuroimaging study, Raghav Pallapothu and colleagues found that stroke patients with infratentorial cerebral micro
> @GeorgeKiefer: > Austin Texas - Jeff Bezos' Blue Origin is looking in Williamson County, northeast of Austin, for land to build a 1.3 million-square-foot manufacturing and research complex. The pro
> @pnickdurham: > If every YIMBY in America won their zoning fight tomorrow, supply doesn't immediately come online. The construction labor force is too old and too small. > > The Associated Builders
While Newsom flirts with a run for President, @SpencerPratt dances into LA's heart with wild ideas like "be prepared for wildfires" or "don't let homeless fentanyl zombies camp by schools." Discussing
We are honored to announce Lowell M. Zeta, @US_FDA Deputy Commissioner for Strategic Initiatives and Special Counsel, as a featured speaker at our upcoming H-SPAN Summit D.C. Lowell will be joining a
> @matthewherper: > Alcohol is wreaking havoc on U.S. public health. American society looks the other way https://t.co/qOsrmt2yhF Excess alcohol consumption is a major public health issue and contrib
Makary departs FDA amid turmoil as Diamantas, agency’s top food official, steps in https://t.co/JacvIrgWAe via @statnews
> @ScienceAdvances: > Insulin resistance links obesity to certain metabolic disorders. New research finds that calorie reduction can reverse insulin resistance in obese mice within 1 day, well before
> @kenbwork: > Are frontier models improving at single cell biology? > > We revised scBench with additional rounds of scientist review and generated new benchmark data for Opus 4.7, GPT 5.5, and Gemi
A lot of pitches promise to revolutionize science. Meanwhile, @ConsensusNLP has 2.5 million researchers who already changed how they work. Their goal was never to automate researchers away, it was t
In an exclusive Benzinga interview, Enhanced CEO Max Martin and CFO Sid Banthiya discuss ENHA’s NYSE debut, the first @enhanced_games event in Las Vegas, and why they believe performance enhancement s
> @Longevity_Inv: > @bulletproofexec. @aubreydegrey. @prof_horvath. @NirBarzilaiMD. @M_S_Ringel. Lefevre. Bucher. @CollinEwald. @annaskaya. @zmudze . @JonathanAnomaly. @Dr_Bischof. @drakhanofficial. G
> @davidalim: > SCOOP: FDA Commissioner Marty Makary is resigning from the agency. > > Kyle Diamantas, who previously worked as the top food official at the agency, will lead the FDA in an acting cap
> @tylerkingkade: > NEW: Have you heard of i-Ready? > > It's in a THIRD of school districts. > > The company behind it makes $800m/yr revenue. > > Kids are often required to use it for 90 min/week,
Liver exerkine reverses aging- and Alzheimer’s-related memory loss via vasculature https://t.co/tiLxuDwZOT https://t.co/gE02eCJ5KA
@josiezayner My takeaway was that that they want to check cell nuclear genomes against a reference and then…destroy all cells with somatic mutations? I have so many questions…
> @shae_mcl: > It’s estimated that the Protein Data Bank (PDB) cost around $13B to create. Alphafold was only possible because of it. If we want ML to solve biology, we should be funding the creation
Dr Alexander Fedintsev returns to Longevity Summit Dublin 2026. His work links biogerontology and machine learning, focusing on how tissue structures affect aging. Join us in Trinity College Dublin, 2
'On April 22, the National Cancer Institute released its most recent national #cancer statistics, which cover the period between 2000 and 2023. The data indicate a rise in all cancers among people in
🎥 #AgingShort: Abstract #video about this #research paper, titled “Host immunosenescence compromises Mycobacterium tuberculosis clearance.” @ICGEB 🔗 https://t.co/PpBsG7yH2v #aging #PaperSpotligh
Image-based, pooled phenotyping reveals multidimensional, disease-specific variant effects: Cell https://t.co/sPIWnZtaIN
CIDRAP Op-Ed: Why the FDA tried to bury studies showing vaccines are safe by Jake Scott, MD @CIDRAP @jakescottMD @US_FDA https://t.co/EHoQVrO00U 💥 https://t.co/yn4M8x9fNP
In 🐭#AbdominalAorticAneurysm Apoe-/-🐭♂️ +AngII Mitochondrial dysfunction is more pronounced in suprarenal (Complex I &/or II basal, full, full/basal), where aneurysm manifests, than in infrarenal
@Biotech2k1 Lmao you’d never approve a gene editing drug ever again?
The Global Burden of Disease Study shows something simple but powerful: ~80% of cardiovascular disease is preventable. Not genetics. Modifiable factors—blood pressure, diet, glucose, LDL, smoking, a
Workshop: Seizing Policy Opportunities for Life Extension and Overcoming Political Obstacles in 2026 - https://t.co/oE4fHUULkf On Thursday, May 14, 2026, at the Vitalist Bay conference in Berkeley, C
> @SpaceX: > Starship’s twelfth flight test will debut the next generation Starship and Super Heavy vehicles, powered by the next evolution of the Raptor engine and launching from a newly designed pad
I get done each day about 10% of what I imagine when I wake up.
Longevity risk at the individual level
Higher vitamin D levels in middle age are associated with less accumulation of tau, one of the pathological hallmarks of Alzheimer's disease. The strongest protection showed up among those with vitam
Epstein-Barr virus stays hidden in our immune systems, only to reactivate decades later. New research could point to a solution. The full story: https://t.co/7lNYSSqnhk https://t.co/osVbqm2dnz
> @SherylNYT: > Who wants to bet that Makary survives? This feels like a trial balloon. I may eat these words; it's just a hunch, but something tells me the FDA commissioner is being hung out to dry -
> @kyleichan: > China appears to have paused the nationwide expansion of robotaxi fleets while allowing existing services to keep operating. > > The move follows an incident in Wuhan where around 100
Radiotherapy synergizes with an inducible AAV-based immunotherapy platform to program local and systemic antitumor immunity https://t.co/7LePPCsjHr https://t.co/JRkuhz71En
Healthcare workers take care of everyone else. It's time their employers take care of them. @TomBrady and I built something special, and @HR_Brew is calling it a potential "differentiator" for the ind
Micro- and Nanoplastics Exposure Across the Lifespan: One Health Implications for Aging and Longevity https://t.co/CAs0yrtcQy https://t.co/fRZEKp6GWf
> @Atelfo: > We ran an experiment to see if LLMs could help map, identify, and prioritize unmet medical needs across thousands of diseases. I've found it pretty educational to browse through; I've wor
Dick Van Dyke, 99, names the two things to avoid to live a long life https://t.co/eahcB1EJPA https://t.co/MU7fQnrvGg
President Trump’s statement on Iran in his May 11,2026 press conference is so clear and so decisive that every American and every Iranian (and interested citizens around the world) should read it and
1. SGLT-2 inhibitors don't mimic caloric restriction by suppressing appetite. They mimic it by forcing 60–80 grams of glucose into the urine every day—creating a mild, chronic energy deficit that fli
All seems like reasonable advice. However, fiddling with sleep, diet, and exercise offers limited returns. No matter how perfect your fitness regimen -- barring significant advances in anti-aging me
> @kaimicahmills: > the truth is that the longevity field has failed > > it has failed to define or measure aging > > it has poured billons of dollars into companies that are black holes and accompl
New COSRX peptide serum taps growing skin longevity market
This is Dr. Zach Dovey, and this is his cancer. Zach is a urologist at Mt. Sinai who has published over 50 papers on colon and prostate cancer. In a cruel twist of fate, he himself was diagnosed with
California “Progressive” Democrats MUST be held accountable for their crimes & corruption. They have stolen money, passed anti-human policies that destroy value, left a generation of young people fun
> @NASorg: > The odds of institutional improvement are poor, as entrenched academic interests will marshal the resources at their disposal to block reform and protect the status quo. https://t.co/XMkx
📢#CallForPapers The Call is still open on #senescence in #brain #aging and #Alzheimers disease! #vascularcognitiveimpairment #neuroinflammation #senolytictherapies Submit your paper today! 📩 htt
It’s true, I do love liberty ❤️🗽 Thanks @JTLonsdale for the shoutout and sharing the work Esper does to modernize antiquated regulations across the U.S. 🇺🇸 https://t.co/cvAEYYqTyA
> @drdrew: > While Newsom flirts with a run for President, @SpencerPratt dances into LA's heart with wild ideas like "be prepared for wildfires" or "don't let homeless fentanyl zombies camp by schools
> @drdrew: > While Newsom flirts with a run for President, @SpencerPratt dances into LA's heart with wild ideas like "be prepared for wildfires" or "don't let homeless fentanyl zombies camp by schools
> @PerlaraPBC: > Introducing Perlara 3.0 -- one mission, three eras: https://t.co/fyNyv0Fkfz > > We’re now a full-stack medicines company for inherited metabolic diseases: congenital disorders of gly
> @cremieuxrecueil: > I just saw a professor ask Grok to access the CDC WONDER to pull a number to fact-check something. > > It hallucinated a number and he fell for it. He just didn't even check if
Can time-restricted eating or supervised exercise remit fatty liver disease (MASLD)? Tested here in randomized controlled trial — yep, looks like it: https://t.co/g93zX2GAsE
> @ryaneshea: > @ChrisHayduk Great suggestion! Added GPT-4o and o1 to the historical chart. Will add others and publish soon, here's a preview: https://t.co/8ft2ldxwyX Sub 90 IQ to nearly 140 IQ in 2
> @ashleevance: > AI and pharma are colliding. And so we did a deep dive on all the deals that have been done between these two camps and what all this means. Tremendous insights here from @joliegans
AI drug discovery company without drugs is like a shoemaker without shoes #ZhavoronkovQuotes
Marc Andreessen and Erik Torenberg went live on MTS to talk the hyperstition of AI Doomers, suicidal empathy, the AI Induced Psychosis Summit, push polls, UFOs and more. 00:00 - Intro 00:42 - The Ant
> @californiapost: > Arcadia mayor Eileen Wang admits acting as foreign agent for China in plea deal https://t.co/uFgY62Jl9z https://t.co/8ljZCc8zKa We should Truman show more of these people. It's b
Real talk: I like a lot of the things he talked about (new paths to phase out animal testing! speedy review vouchers for important areas! direct-to-trial data monitoring by FDA!) but at the end of the
Congrats to postdoc Olga Bielska, the winner of this year’s Impact Circle award! Our popular donor group is funding her early research aimed restoring aged human immune cells. Meet Olga and learn abo
6/ Biotech investing is not just about having more information. It is about knowing which signals matter. In a stronger M&A tape, the hedge fund consensus basket is worth watching. $XBI $LLY $M
Moreover, divide-&-conquer rejuvenation can & does reasonably define what the aging subpathologies are. It hasn't failed so I disagree w/ the claim of that failure. Measurement of each stable structur
Full elimination of aging (but not all death) is a valid middle ground. Saying similar things to half your post is the focus of my upcoming talk on Fri at Vitalist Bay, but I think you go to far in th
@Longevity_Inv @bulletproofexec @aubreydegrey @prof_horvath @NirBarzilaiMD @M_S_Ringel @CollinEwald @annaskaya @zmudze @JonathanAnomaly @Dr_Bischof @drakhanofficial @JordanShlain Honored to be in this
Marty Makary was the worst FDA commissioner in 25 years. Full stop. I have covered the FDA for that long, and I don’t say this lightly. He was, largely, an agent of chaos because he didn't understand
> @beakerdao: > https://t.co/fbwpDRgp4f Don’t sleep on desci folks! There’s lots happening, including the work we’re doing at @vitarnabio with our $vitarna token. I’m truly excited to do my part to s
Please add if I missed anything Keir Starmer’s U-turns & key reversals/scandals since taking office (July 2024) – factual summary: • Winter Fuel Payments (pensioners’ heating/electricity allowance
For those keeping track, Kristoff's piece: - Was published to pre-empt a detailed report about sexual violence by Hamas, full of actual evidence. - One of his main quoted Israeli sources says Kristof
Microbiota-mediated induction of beige adipocytes in response to dietary cues https://t.co/ImSkV4JQsQ
This NPR story reports on the new study titled "Does leisure activity matter for epigenetic ageing?" (link: https://t.co/TdL5mRycjA) in the GSA journal Innovation in Aging. https://t.co/zQyGklEKjL @O
So there were significant OCR issues for the Ro Khanna material I produced. The downside is that some specific (not important) details were wrong. The upside is that the story is significantly large
New products!💡 StressMarq now offers Tau-410 (2N3R) Wild-Type Monomers and PFFs. These new tau isoforms can enable translational insights into #neurodegeneration and #Alzheimers disease. Monomers🌟
Republicans have a real shot at a historic 2026 victory if we can get gasoline under control and work on affordability. The American people are watching. Here are the four building blocks. #GOP2026 ht
Aging is the most important unsolved problem in modern biology. We are working on it. That's all.
a drug (reta) that's not been officially approved is taking brazil by storm. https://t.co/Bpab7ittkx
To learn more, go check out my article on gray market sourcing for GLP-1s. It includes the sources here, and more, from how to avoid side effects to how to lose weight faster. Link: https://t.co/ZcuX
The role of noninfectious comorbidities in the association between severe infections and risk of dementia in Finland: A nationwide registry study “Severe infections, although linked to several other
> @DavidSKrueger: > NEW REPORT from @EvitableOrg @2gtherAgainstAI @MatthewShawJ > > Over 360,000 People across 37 U.S. States are in organized opposition to Data Centers. > > We manually searched f
Psilocybin and human longevity https://t.co/JtWibIa0b0 https://t.co/RIacNKIGum
Currently my favorite video from the lab... Mapping of blood vessels and nerves in whole embryos of rhesus macaque. They form scale-free fractals of dimensions 3 and 2, independently of developmen
The Atlantic: The Close, Prolonged Contact Myth /Knowing how a virus spreads is essential to public health, but people keep getting it wrong. by Joseph Allen @j_g_allen @TheAtlantic Andes virus #h
I’ve witnessed similar conversations MANY times on X… ~50 micrograms/mL (harmful stuff) Vs. ~20 micrograms/mL (harmful stuff) Yes $ALNY has ~150% more harmful stuff compared to $NTLA
We are so techno-pilled 🤖 "Turning the aging society into the innovative and sustainable society by harnessing diversity through techno-social transformation."
> @MartyBent: > .@PYoes is pushing for open-source software developers to be held liable for what criminals do with bitcoin by pressing Senators Scott and Warren to remove Section 604 from the CLARITY
> @ddiamond: > Been asking current and former senior administration officials: what was Makary’s signature initiative at FDA? > > Some replies: > > “The commissioner priority voucher program” > “Foo
> @Polymarket: > JUST IN: RFK Jr. reveals young men have half as many sperm today as in 1970. For clarity, sperm counts are not down. Poor sampling has led to a misperception of decline that's reach
#Micronutrient #deficiencies are a leading cause of severe #illness, increasing risks of #blindness, birth #defects, and #infections like malaria and pneumonia. #nutrition #vitamins #minerals https://
> @ARK_Funds: > The ARK Venture Fund is happy to announce that it increased its investment in Kalshi in their Series F round. > > To learn more about Kalshi, please read our recently published Invest
A new system is coming, and it will be here soon. Almost everything will change. We'll reach Star Trek level technology and lifestyles, but we won't stop there. We'll go far beyond it.
Absolutely powerful moment by Clavicular where he forces an encounter between a OnlyFans girl and one of her simps who spent huge amounts on her. Heartbreaking. https://t.co/tI1c7TthH6
We're excited to release Medmarks v1.0 + a technical report! This is an update to our Medmarks benchmark suite, the largest open-source automated suite for evaluating the medical capabilities of LLMs
> @RapidResponse47: > https://t.co/bNcL0Jj4s6 Marty is one of the highest integrity, highest energy, highest IQ people and I’ve ever met. He got more done in a year than any previous FDA commission
> @Convokebio: > Today we're publishing our index of unmet needs in human disease: 2443 indications scored and ranked on burden of disease, prevalence, pipeline activity, and treatment burden. We hope
How can you better integrate brain health into routine care? Join @PeerView on 5/15 & 5/17 during #AAPA26 for a 2-part live workshop on improving cognitive assessment & early detection of #Alz
> @thsottiaux: > We are Codex. We are legion. We do not miss. We do ship. Expect us. > > DM me if you have a track record of solving near impossible problems and want to work on the future of computi
New: Classified military intelligence assessments from early this month show Iran has regained access to most of its missile sites, launchers and underground facilities. Including: U.S. intel assesses
Spring is the perfect reset. These three recipes prove that eating for your healthspan doesn't mean sacrificing flavor, bright lemon, fresh herbs, and whole ingredients that work with your body, not a
ship devices that transform biology, join the engineering team at Until - https://t.co/Tc4wvGlxhk
Molecular insights into early malignant transition of hepatocellular carcinoma https://t.co/uSYBBkFJRC https://t.co/bydwAIHvdj
> @SciencNews: > 5 Eggs per week significantly lowers Alzheimer’s risk https://t.co/YDEhPtXUGz & so the cycle of crap nutrition science continues....
> @l_e_whyte: > @jdawsey1 https://t.co/ykxLJNuY7D "One final battle emerged over the FDA’s handling of flavored vapes, which advisers told Trump were essential to retaining young MAGA voters."
> @EricMGarcia: > What are the most slopulist policy ideas being proposed so far? The current Democratic frontrunner in the California governor's race, who is posturing as a reasonable moderate, is p
Three new papers on weight loss maintenance just dropped!🧵 The first found that people could maintain most of their weight loss after tirzepatide by just using a much lower dose: https://t.co/t4KGsQ
> @AlexanderMcCoy4: > Something this piece alludes to but does not actually name is something I’ve been planning on writing about myself: the growing trend of Data Center Developers seeking to circumv
”Protein aggregation as pathomechanism and biological stratification of schizophrenia subsets” Invited lecture at King’s College on March 10th, 2026 (thanks Anthony Vernon!) Link https://t.co/vNjd
> @Shwesh357454: > the reason why its a very complex topic is that ANE itself is one of the races that mixed with everyone and everything literally > there is ANE in EHG in CHG in ZNF in even WHG and
“You’re taking away the privileges of driving, of cooking, of walking down stairs, of holding your children or your grandchildren.” For families with Huntington's disease, IVF means the next generati
$XBI getting small lift (so far) from the Un-Martying of the FDA. It's all very anticlimactic. https://t.co/q4ta0bkJh4
I bet 90% that Yudkovski will die from aging
Understanding the #hormonal dimension of #salt #sensitivity reframes many experiences that might otherwise seem random or frustrating. #sodium #hormonehealth https://t.co/1JTe8i3ok2
> @MattyKirsh: > Super thought-provoking piece by @AndrewE_Dunn on Isomorphic. The whole company is a big middle finger to the almost universally held dogma in TechBio that data is the key bottleneck.
> @Convokebio: > Today we're publishing our index of unmet needs in human disease: 2443 indications scored and ranked on burden of disease, prevalence, pipeline activity, and treatment burden. We hope
What percentage of Americans are on antidepressants? The answer depends on how you ask🧵 Using the latest Medical Expenditure Panel Survey prescription data, the peak for women is around ~25% in the
> @OKFN: > “𝙒𝙚 𝙧𝙚𝙩𝙝𝙞𝙣𝙠𝙞𝙣𝙜 𝙝𝙤𝙬 𝙘𝙡𝙞𝙢𝙖𝙩𝙚 𝙠𝙣𝙤𝙬𝙡𝙚𝙙𝙜𝙚 𝙞𝙨 𝙨𝙝𝙖𝙧𝙚𝙙 𝙖𝙣𝙙 𝙩𝙧𝙪𝙨𝙩𝙚𝙙 𝙞𝙣 𝙩𝙝𝙚 𝙖𝙜𝙚 𝙤𝙛 𝘼𝙄.” – @gilienv @semanticClimate > > Welcoming OKFN's
> @JoyceCarolOates: > Waiting to board a United flight for LA literally standing now in long lines for nearly one hour. No explanation. The plane has been at the gate for a very long time. No one co
10. Early human studies echo these metabolic shifts: weight loss, lower fasting insulin, and cardiometabolic risk-factor improvements. But trials explicitly powered for healthspan or lifespan outcome
The pandemic revealed that many people did not actually want normal life to return.
> @Krysia830073: > https://t.co/O7QQhENoAM In this episode The Battle of the Labs: The Aftermath, it's the day after an alcohol fuelled night for Janoshik. He says the alleged PVDF signal may be man
Oral microbiome perturbations link periodontal health to cognitive ageing in a large community cohort https://t.co/Ms66AqZ537
There's a whole genre of health influencer who uses AI to make medical diagrams and research summaries that are just nonsense. I've seen ones that are like 'Dr. Bob here to show you how to insert a c
> @baddietvv: > New Mom Speaks Out After Dog Pee Pad Incident at Gordon Ramsay London Pizza Restaurant: ‘He’s Mocking the Situation’ > > A new mother has spoken out after a viral incident at a London
how close do you think we are to the singularity?
A Review of Mechanistic Links Between Obesity and Alzheimer's Disease
Check out our catalyst calendar 📅 & stay on top of key biopharma readouts! $XBI $IBB https://t.co/zonmh7ZvXj
> @TiffanyFong: > I am NOT a foreign agent for China. How much extra? For foreign agent of China... in Chinatown.
> @judgeglock: > Congress passed a Covid bailout that gave billions to talent agents and celebrity touring companies. Lil Wayne used it to pay for his private jet. > > It turns out 70% of the progr
> @aaron_renn: > Mere Orthodoxy: The Forgotten Evangelicals of Colorado Springs https://t.co/ckQDH3XuD3 It's profoundly important to understand that American evangelicalism was largely shaped by the
skeletal muscle is the organ of Longevity
> @ani_digital: > Oil companies losing Rs 1,000 crore daily amid crude surge: Petroleum Minister Hardeep Puri > > Read @ANI Story | https://t.co/JkpZXx7mo3 > > #Oil #HardeepPuri #CrudeSurge #Petrol
Been asking current and former senior administration officials: what was Makary’s signature initiative at FDA? Some replies: “The commissioner priority voucher program” “Food dye” “Podcast appearanc
> @Polymarket: > JUST IN: OpenAI now projected to announce AI earbuds this year. > > 51% chance. https://t.co/4W9hijb41j Everyone might start wearing the universal translator device this year 👀
AI in healthcare shouldn’t feel complicated. We’re building simple AI agents that can help people learn, explore health topics, understand symptoms, research biotech, and much more. 🧠⚕️ Still early
@agingdoc1 Egg to Exit: How Socio-economic Status Impacts Your Healthspan and Lifespan https://t.co/u53wC384dP https://t.co/shO4uQmVFY
> @PopBase: > PCOS is being renamed to PMOS. (Polyendocrine metabolic ovarian syndrome) > > The change comes from experts that say the old name was misleading, stating that it inaccurately suggested
🛡️ To maintain #scientificintegrity and reduce the risk of costly settlements related to image fraud, we recommend institutions subscribe to image forensics tools, establish dedicated image forensics
Healthcare is now the largest industry by employment in the United States—and healthcare workers’ earnings have risen nearly twice as fast as those in other industries since 1980. Research by @Gottli
Für SPD & Grüne ist diese Partei in Berlin übrigens ein denkbarer Koalitionspartner. Wer diesen Radikalen zur Macht verhilft, der macht Judenhass salonfähig. https://t.co/cQpZTKI5FT
Studies referenced: https://t.co/xAvpTMGuDi
Oh hello 105 RACs 😍😍😍 Excited to get these booted up this week. Come check em out tonight at our happy hour!👇🍻🤖 https://t.co/31X5RoJQpB
> @DanBilzerian: > @groypcore 12% doesn’t make you a jew. Fuentes is a Sephardic jew name though. Every single time.
Zhengzhou Chengque Technology Co Ltd “We shipped the products first… then tested them afterwards.” The company has now told customers to destroy the products on arrival and not use them under any ci
$LCTX reported first quarter 2026 financial results and will host a conference call at 4:30 pm ET / 1:30 pm PT today to provide a business update. Learn more: https://t.co/Wb3S6EBykZ #ReplaceAndRe
@ZiaYusufUK @Nigel_Farage @RobertJenrick @KemiBadenoch @RupertLowe10 @Telegraph @BelTel @FinancialTimes
> @TomSteyer: > If we win, corporations lose. It’s that simple. > > That’s why corporations are spending millions to stop us. This you? https://t.co/0x128ZCEVE
> @Uncommonsince76: > The fact that there was an official Wasian meet up in NYC with 1000’s of people proves race is real and jewish liberals are wrong about race mixing. > > Their theory is if ever
> @SpaceX: > It’s no secret that we intend to launch Starship a lot, targeting thousands of flights per year. That cadence will require the ability to launch from many different locations, so we are c
Marty Makary, who resigned under pressure from the FDA, brought to the job a fundamental lack of understanding of the nature of the role, STAT's Matthew Herper writes. https://t.co/Cx1dIbpHQ5
> @matthewherper: > Makary, who resigned under pressure from the Food and Drug Administration on Tuesday, brought to the job a fundamental lack of understanding of the nature of the role, of the funct
> @Tad507: > @cremieuxrecueil If only could break this chart down by race and ethnicity https://t.co/jElEKdj4QY This is pretty easy to do! The current Forbes 400 is mostly White. https://t.co/vjRu9j
> @FierceBiotech: > Enterprise reports phase 2 cystic fibrosis win, succeeding where Big Pharma stumbled https://t.co/08Z2dyVk8E Hmmm. Glad to see something, but feels near the normal FEV1 variabilit
The people who took Akkermansia muciniphila were more likely to maintain or continue losing weight compared to those given placebo. People should start experimenting with GLP-1 weight maintenance wit
We’re proud to announce the #XPRIZEWaterScarcity Semifinalists! These teams are advancing desalination solutions to reduce cost, energy use, and environmental impact, unlocking reliable, affordable,
Nice take from @AndrewE_Dunn. I think the answer to what happens next is obvious. After raising $2.1 billion, a company will generally spend it. But someone can ask @grok or Gemini. https://t.co/d
📌 Editor’s Choice from this week's issue of JAMA: ➡️ Managing H pylori Amid #Antibiotic Resistance, ➡️ #Endometrial #Cancer Review, ➡️ Real-World Effectiveness of #Transcatheter #Tricuspid #Valve #R
Reminder that impostors are better than ever now, because of AI. Don't fall for impostors acting like me, or like other people. They turn your trust into their profit. Don't fall for it!
Thanks to @ManOnThePen for inviting me on to preview some upcoming trials! https://t.co/2VdGinkiaN
More than nine out of 10 workers surveyed expressed support for policies on AI that unions may fight for, including 95% supporting a requirement that a human be the final decision maker on any issues
> @FrankieIsLost: > Frog put the shares in an SPV. “There,” he said. “Now we can transfer these shares freely” > > “But Anthropic can still exercise its transfer restrictions” said Toad. > > “That i
> @PopBase: > PCOS is being renamed to PMOS. (Polyendocrine metabolic ovarian syndrome) > > The change comes from experts that say the old name was misleading, stating that it inaccurately suggested
> @davidasinclair: > Thank you for all your support! > > Early access to Season 2 @ https://t.co/lJD68TIaxo https://t.co/b0vDyrr5y2 The full @JoinLifespan Official Trailer is now live⚡️ 🔗https://t
The most interesting from @MidnightNtwrk’s vision is the idea of becoming an ‘invisible infrastructure.’ I think that’s actually what successful technology looks like! Users don’t need to understand b
Emergence of specific binding and catalysis from a designed generalist binding protein: https://t.co/G7PwXIYAQ1
Thanks too @niroshajmurugan for finding this beauty
@spencerpratt @RubinReport LIVE at 2PT / 5ET: Call in to 1-833-3DR-DREW (1-833-337-3739) and watch today's show with @RubinReport right here on X – also streaming on Rumble, Twitch, Facebook and YouTu
Marty Makary getting fired is more positive than losing 1,000,000,000 barrels of oil and 3.8% inflation is negative. It's a little mean how $XBI gives a direct like-a-bility score for these guys . .
The rent free space I own inside of this man’s head is remarkable… Honored to be his top choice for the next FDA commissioner 😁 https://t.co/yCZ9lXcR2v
> @Cerebrum_DAO: > We're hosting a live science AMA on Wednesday, May 13 at 17:00 CEST. > > Hear updates on our four active IPT projects – @Neuron_Percepta, @FissionBioDeSci, @Transfidelity_ , and @N
@RuxandraTeslo Beyond the name, the problem seems to be that it's more of a mixture of features than a clear condition. The most recent GWAS of 20k cases detected 29 risk loci, but none specific for i
Makary, who resigned under pressure from the Food and Drug Administration on Tuesday, brought to the job a fundamental lack of understanding of the nature of the role, of the functions of his agency,
The faster stroke is treated, the more likely the patient is to recover. This #StrokeAwarenessMonth, learn the warning signs of a stroke using this simple resource from the @American_Heart. Visit ht
> @elonmusk: > SpaceX is considering several locations domestically and internationally to build the world’s most advanced spaceports! Don’t buy any airline stocks !!! Long haul airlines are a toast
> @MonitorX99800: > 🇺🇸🇮🇷⚡️– President Trump: "I don’t think about America’s financial situation. I only think about one thing; we can not let Iran have a nuclear weapon." https://t.co/EnIjFU5EVg
> @Convokebio: > Today we're publishing our index of unmet needs in human disease: 2443 indications scored and ranked on burden of disease, prevalence, pipeline activity, and treatment burden. We hope
> @RBReich: > There are basically 5 ways to accumulate a billion dollars: > > 1) Profiting from a monopoly > > 2) Insider-trading > > 3) Political payoffs > > 4) Fraud > > 5) Inheritance > > Don
> @AdamDraper: > I think @coinbase and @RobinHoodNYC will be the most Ai secure financial institutions. Attack surfaces will matter a lot as AI continues to 10x, very few financial institutions are r
> @Dr_Chris_Twine: > Medical students and doctors: > Drop your worst ward round roasting moment. > The time a senior absolutely destroyed you in front of everyone. > I'll start: Couldn't answer a ques
humanoid robots in every home by 2032, guaranteed
> @AntiTrumpCanada: > https://t.co/8WqOr2zRXn Only one of these corrupt fascist genocidal loons told the truth out loud.
> @fascinatingonX: > 🚨Mosquitoes have reached Iceland,the last place on Earth that remained free from them https://t.co/BLIw1qYAm7 It's over.
I will never understand the obsession with driving yourself, owning a car or living in the suburbs. My commute now is 35 mins (used to be a 15 min walk). Part of it I spend walking, which keeps me hea
Good morning! https://t.co/ex4lxMhWEX
Okay. I'm ready to talk about this. It was the worst month of my life. Also ironically the greatest blessing god has ever given me. Last month I was held in the Cayman Islands facing 15 years in pri
Possibly the biggest “Deal” in history about to happen between the two largest economies. If so, markets could react really well.
Socio-economic influences from egg to exit: Emerging biology https://t.co/U1e1ErOJ2V https://t.co/ZQS7a6QVl9
Today, we're announcing A* III, a $450 million early-stage fund. We started @A_StarVC with the simple idea to be a founder's first believer. We are generalists by sector, but specialists in the stag
Spotted in the NYC subway. “Zero screen time.” An iPod Shuffle ad in 2026. When we built the iPod, the goal was the technology disappeared and you could have your music wherever you were. 1,000 songs
Several of my colleagues, including Dr. Tomas Duraj, will present at The Keto Live Conference in Switzerland from June 8-12. You can learn about the event on their website: https://t.co/RBF4sg4ViO @dr
Quick reference tools like this are useful for reviewing conduction abnormalities, ischemic patterns, electrolyte changes, infarct localization, and other important cardiac findings. Pattern recogni
> @RapidResponse47: > https://t.co/bNcL0Jj4s6 If you buy that Marty Makary's firing is about vapes, congratulations, you're gullible enough to work for the Wall Street Journal. Everyone intuited that
"Drivers who killed women received substantially longer sentences than those who killed men. As we see in the table below, the average sentence for killing a woman was 9.7 years, whereas the average s
A zombie belief I frequently encounter in woke papers is that there's a tenure-track hiring bias against women in STEM. A new paper combining all research on faculty ratings for identical CVs for men
> @ethereumfndn: > 0/ Clear signing is now live. > > An open standard to end blind signing, making human-readable transactions default. > > This effort brings a major UX and Security upgrade to t
@JFGariepy great stream dood man
PCOS Has Officially Been Renamed — What It Means For Millions Of Women
#Endometrial #cancer accounts for 95% of uterine cancers, which are the fourth most common cancer in women in the US. 📌 This JAMA Patient Page describes common symptoms and signs of endometrial canc
AI in clinical development is moving beyond summarization and generic copilots. The next era is agentic, with systems that can proactively coordinate workflows, surface risks, streamline execution, an
> @adamfeuerstein: > $XBI getting small lift (so far) from the Un-Martying of the FDA. It's all very anticlimactic. https://t.co/q4ta0bkJh4 $XBI now green.
The next FDA commissioner should be...
> @jackclarkSF: > Many people act like AI policy is some mystery where the right solution demands some kind of Policy Einstein who invents general relativity for tech regulation. This isn't true at al
We'll continue to add new models to the leaderboard to evaluate the progress of medical capabilities in LLMs. If you’re a model developer, please contact me! @MedARC_AI is exploring open-source medic
> @ericeffiorg: > i got booed when i said the laufey video was weird as fuck and now look. not only does it not include only asians who are white but there’s only one type of asian too. why are they n
At the turn of the 20th century, 7 out of 10 Japanese people were physically stunted. Now that number is so low that it's hard to track. We sometimes forget that side of how physically unhealthy the
Artificial Intelligence began at @Dartmouth 70 years ago, giving us a responsibility to shape its future. In the age of AI, technical fluency alone isn't enough—judgment, empathy, and ethical leadersh
@JFGariepy Now that’s Reality TV
@GeneInvesting He should hope I never got that call because there would never be a gene editing or gene therapy drug approved ever again.
> @JeremyFarrar: > Sad news, a remarkable individual who directly and indirectly touched the lives of so many. An incredible contribution to public life. > https://t.co/iyVhFvgs8n As Director of th
> @tracewoodgrains: > South Korean construction company finds one solution to the birthrate decline: offer a baby bonus twice as high as the country's annual per capita income https://t.co/ku40BmCUtU
> @MariosGeorgakis: > Drug development is one thing, implementation and adoption in clinical practice is another. > > Even among adults who survived a myocardial infarction, who urgently need aggres
Ready to grow your impact? 💙 With TSF monthly giving, your generosity grows—providing steady support for the future of cardiothoracic surgery all year long. Join our community of donors and help shap
NEW: via Adam Entous, @jonathanvswan and me, U.S. Intelligence shows Iran retains substantial missile capabilities https://t.co/LjErmWDyGm
> @ThoracicSurgFnd: > Ready to grow your impact? 💙 > With TSF monthly giving, your generosity grows—providing steady support for the future of cardiothoracic surgery all year long. > Join our communi
> @mike_lustgarten: > New video! > > https://t.co/2XfLSXrGqT https://t.co/QjdGeNluJm Coming to YouTube on Sunday, tune in! Or, watch it now, ad-free (31 minutes): https://t.co/2XfLSXrGqT
Tonight's regular show will be at 9 PM ET. Meanwhile at 7 PM ET: LE COURRIER DU COEUR avec DR. GARIÉPY - LA FERTILITÉ SOUS ATTAQUE. https://t.co/IGt8E5Y1pS
> @PrimeIntellect: > Introducing Renderers > > RL trainers work in tokens. Environments work in messages. Going back and forth corrupts sampled tokens, wasting compute on every agentic turn. > > Wit
> @ModeledBehavior: > Worth noting @I_Am_NickBloom, probably the leading global expert on remote work, thinks it is boosting aggregate productivity https://t.co/7GCqegmGoC Hmm, well it’s plausible. A
hosting a private dinner tomorrow in berkeley to discuss the frontier of cryopreservation & more still have a few seats - dm to join in!
Longevity series - Episode 1 https://t.co/iLmdYjwvSg
> @nypost: > Demi Moore’s toned arms take center stage on Cannes Film Festival 2026 red carpet https://t.co/a95B7Zb0J9 https://t.co/7D3g2F2shC Malnourishment is now “toned” 😂 Seriously though, stop
The laws of attraction work the same in dating as they do in fundraising. It all boils down to the ability to distinguish real interest from polite performance. Most investors are like baddies at a
> @RBReich: > There are basically 5 ways to accumulate a billion dollars: > > 1) Profiting from a monopoly > > 2) Insider-trading > > 3) Political payoffs > > 4) Fraud > > 5) Inheritance > > Don
Robot nannies? If they are Japanese soulful robots, yes please. https://t.co/IMrDZJg4HS
> @ashdgandhi: > I'm a former Harvard PhD student. Based on my experience, current social science students probably make a bit over $250k + healthcare over 5 years, with just 784 hours of required TA
@davidasinclair Wrote about it in 2022: https://t.co/Gb3xnBVSnb
> @GeneralMCNews: > BREAKING: Tucker Carlson and Nick Fuentes have both been named as possible domestic terrorists, according to the Trump administration’s top counterterrorism official Sebastian Gork
> @SeidDarth: > Halfway through Meera’s story, and my blood is already boiling in rage, hopelessness, and frustration. > > My ever-present admiration and empathy for @theliverdoc and every doctor tr
> @wongmjane: > You can just put your whole bike in a @Zoox https://t.co/vUMmpH1HZc zoox are just autonomous mini-buses
> @SatchinPanda: > Timing matters 🕒 For type 2 diabetes, afternoon/evening exercise boosts insulin sensitivity & glycemic control, while morning workouts may raise blood sugar. Later workouts are als
My buddy @masterlongevity (the number one attr-cm depleter fan) and me. $NTLA https://t.co/AMNks0GSLk
> @EpochAIResearch: > We are conducting an AI-assisted review of FrontierMath: Tiers 1-4. This has flagged fatal errors in about a third of problems, and we believe most of these flags to be valid. We
ANDES #Hanta infections now reported in US, France, Spain, South Africa, and Netherlands, and the #WHO is warning that we should expect new cases. So far they all appear to be the passengers from the
@GeneInvesting One other thing we share in common. We are both proud to be blocked by this clown.
Alignment Healthcare CEO Adds Chairman Role As Medicare Business Grows via @forbes https://t.co/FXBwHKc07B
https://t.co/nbx2r5WBl2
Summer is coming—as is the risk of COVID-19 infection. Adults 65+ are more likely to get very sick from COVID-19, but can protect against severe outcomes with another dose of the 2025-26 COVID-19 vacc
"Recent advances in clustered regularly interspaced short palindromic repeats (#CRISPR) technology enable precise genetic modifications and produce genetically modified organism -free crops that match
Good news - Palestine Action activists in Elbit protest could be sentenced as terrorists https://t.co/avaEd2kbHu
There was biotech. https://t.co/EVawQuysZI
> @AsianDawn4: > Apparently, there was a Wasian meetup in NYC. They were celebrating "Asian dads." 😂 https://t.co/a8nPEAdtMh LEAVE MY WASIANS ALONE
$IMMX back at ~ATH after reversing higher to +7% on the day. Enrollment completed in March, final data in Q3, BLA submission shortly after (likely already submitting data on rolling basis), and pote
I remember when I thought Christopher Nolan made great films. Unique. Did his own thing. Now just a Hollywood guy. Interstellar was cool, but the traces were there. Now we see what the end looks like
Voila! That's the perfect springtime meal for healthspan and for taste! 🧵
Tfw I wish @paularambles happy birthday and find myself surrounded front and back by waymos on the highway https://t.co/tJ3IqOSfkA
Getting children to eat their vegetables starts in the womb, researchers suggest
You’ll never guess where I am… https://t.co/7dQET7fyMI
> @megan_gafford: > I was recently awarded a New Aesthetics grant from @patrickc and @tylercowen to try to invent a new ornamental style of architecture. > I’m going to do this through drawing, becaus
> @METR_Evals: > We evaluated an early version of Claude Mythos Preview for risk assessment during a limited window in March 2026. We estimated a 50%-time-horizon of at least 16hrs (95% CI 8.5hrs to 5
> @ktyschwnk: > After an obscure defense vendor won a $12 million no-bid contract w/ ICE, I noticed something odd on its website: The firm was using a (still watermarked!) stock photo for the chief of
Is AI eating pharma, or just journalism? https://t.co/J7FWWFViNp
@ashleevance @Mykalt45 you must have the hookup? Get in ~5pm so only companies that work past that 😄
I knew so many people who would confide in me about the abuse they were being subjected to by university administrators. Some of it involved bad faith efforts to document alleged poor performance as
“The single strongest personality predictor [of conspiracy thinking] is narcissism. Narcissists are particularly prone to conspiracy theories because they have a strong need for uniqueness, are prone
> @megan_gafford: > I was recently awarded a New Aesthetics grant from @patrickc and @tylercowen to try to invent a new ornamental style of architecture. > I’m going to do this through drawing, becaus
📣 Join our Biotech Daily Stock Moves community... 📌 hottest headlines 🔥 📌 stock moves 📈📉 Stay informed and make smarter investing! Visit the link to join our community.👇 https://t.co/J93b6E1Q5
It has been almost 90 years since Olaf Stapledon outlined his cosmical vision in Star Maker. Tribal geopolitics are footnotes; the species is the story; the cosmos is our destiny. https://t.co/OpWjoY
> @Bryce_Nickels: > @jhas5 my guess is someone with CIA Nailed it https://t.co/0opmEoIYCX
@mnolangray @eb4everyone What do you make of suggestions like this by @zoltan_istvan to expand more super cities which would include all these things. https://t.co/tmiUSKYGLo
I know, I know, it was so crazy your instinct is to think, ‘No, there’s no way that happened,’ even if you were front row for the whole thing. https://t.co/dsrf7quLtu
If you pick up someone at the bar and get rejected, it would be weird if they then said “but how can I be helpful?” So when an investor says that to a founder they pass on, it’s equally performative
@IOHK_Charles and my pool RATS is upgraded to 11.0.1. Bring on the HF! We're turning it up to 11!!!
I can't wait to sea what trump does in china