今日摘要生成中
报告将于明天凌晨自动生成，明早九点准时推送
Today’s guests on @FreeRadicalsBio are @jgooten and @omarabudayyeh. As PhD students at @Harvard in Feng Zhang and Aviv Regev’s labs, Jonathan and Omar pioneered research on programmable targeted gen
> @rohanpaul_ai: > AI companies are piling into biotech because biology is one of the few markets where better prediction can directly compound into enormous economic value. > > The economics alone e
Thank god we now have a solution that works for most people. If you got all the obese (BMI >= 30) people on tirzepatide for a year and they stuck to it, you'd cut obesity by about 75%. And these dru
> @kimmonismus: > Demis Hassabis: CRISPR technology can target DNA, but identifying the exact genetic cause of diseases is tough, especially in non-coding regions. AI tools like AlphaGenome are decodi
> @damianplayer: > THIS IS WILD! > > Peter Thiel’s company the “Enhanced Games” got valued at $1.2B before a single event. > > the first one is next month. > > here’s what the headlines aren’t te
> @NornGroup: > Something is bottlenecking AI from increasing the number of treatments that make it to patients… > > @MartinBJensen: “Today, [hypothesis generation, making the drugs, and clinical tri
Thank you for sharing this! In my opinion neuralink’s attempt to treat vision loss is an historical moment in human history - No less! After SpaceX’s huge success, I’m super excited & once again amaze
> @LivnatJerby: > Excited to share our @NatureGenet paper https://t.co/1ove73iCgm #CRISPR activation, Perturb-seq, and a new type of optical screens (in situ Perturb-seq) reveal RNA/protein-based inte
> @davidasinclair: > NEW STUDY finds certain fatty acids selectively kill senescent "zombie" cells. The molecules exploit a fundamental biophysical weakness in senescent cells, a totally new approach.
> @tenobrus: > maybe this is not yet clear, so let me state it plainly: as of right now Anthropic, and really a small number of individuals at Anthropic, has the capacity to directly attack and cause
Sources: Novo Nordisk subscription launch (March 31, 2026): Today Show exclusive. $249/month for 12-month Wegovy commitment through Ro, Weight Watchers, LifeMD, Hims & Hers. Eli Lilly Foundayo prici
(1/2) This #WorldHealthDay, it’s not just about living longer, it’s about living longer, healthier lives. #XPRIZEHealthspan is advancing solutions to target aging itself, helping extend healthspan fo
If you want to help advance this mission, join us. https://t.co/ua0QpsSFY5 Note: Neuralink devices are investigational and are not commercially available or FDA approved. There are no guaranteed bene
Masters Athletes With Abnormal Cardiovascular Findings A Clinical Consensus Statement of EAPC & ACC Mild aortic dilatation 40~45 mm seen in 20% Masters runners/rowers & up to 41% former football/rugb
What, Exactly, Is Longevity Medicine? The field is ripe with opportunity — and opportunism. Here’s how to navigate it. https://t.co/fWNnMbAzye https://t.co/QKP8BOy4iB
> @cleoabram: > What is the real future Google DeepMind CEO @demishassabis is trying to build? > > That's what we talk about in this HUGE* Conversation -- so you can decide for yourself what you thi
NEW STUDY finds certain fatty acids selectively kill senescent "zombie" cells. The molecules exploit a fundamental biophysical weakness in senescent cells, a totally new approach. Could we simply cons
2025 was transformational for Alnylam, from the launch of AMVUTTRA for ATTR-CM to reaching profitability to announcing our next 5 year plan. Hear from our CEO, Yvonne Greenstreet, on what this means
This method to reverse cellular ageing is about to be tested in humans A burgeoning field is launching its first clinical trial to find out whether dialling back cell development can safely refresh a
World held hostage by reliance on fossil fuels, Christiana Figueres warns – and climate health impacts are ‘mother of all injustices’
7/fractyl’s leading obesity Gene Therapy candidate - rejuva, involves injecting a small dose into the pancreas with a proprietary catheter, deploying an innocuous virus to instruct insulin-making cell
> @yaireinhorn: > 1/🚨🚨Wave Life Sciences has presented updated clinical data from its INLIGHT clinical trial of $WVE-007 - Wave’s GalNAc-siRNA candidate for treating Obesity and type II diabetes and
> @biospace: > The acquisition of Tubulis GmbH—Gilead Sciences’ latest of the year after buying Arcells and Ouro Medicines—brings into the fold a novel ovarian cancer candidate that has demonstrated p
0 FDA-approved drugs for extending lifespan. In any species. In history. Resveratrol, NMN, NAD+, fisetin, spermidine. Billions in annual sales. None went through rigorous @US_FDA clinical trials for
The foundry is alive!!! We just released results from our collaboration with Polyphron. Four iPSC lines from diverse donors, manufactured by @CellinoBio, were engineered into structurally equivalent
> @davidasinclair: > New paper @GladstoneInst @UCBerkeley @nvidia reinforces the Information Theory of Aging (ITOA). > > Looking at 175M single-cell gene expression patterns, AI found cells lose the
Most of us have seen someone we love age faster than they should. The biology of aging is no longer a mystery. The science exists to slow or even reverse it. What’s missing? Urgency. Join the April 8
Sources: FDA CVM accepts LOY-002 safety package (TAS): BusinessWire, Jan 13, 2026 https://t.co/0r3br2K4qf FDA CVM accepts efficacy data (RXE): BusinessWire, Feb 26, 2025 https://t.co/Ij16NEsEjE STA
> @TheHillEvents: > "Even cancer didn’t see that kind of geometric pop." 🧬 > > At The Hill’s "Getting a Diagnosis ASAP" event, @GAP_Foundation President John Dwyer discussed the rapid expansion of n
$249/month. Annual plan. Auto-renewed. Shipped to your door. That's not a streaming service. That's @novonordisk's new subscription for Wegovy. Through @ro, @ww_us, and @HIMSS & Hers. @EliLillyandCo
link to the paper at Cell Press Blue, a highly selective, open-access journal 👏https://t.co/lwgqPrhLrT https://t.co/LJri8PjJ76
> @bubbleboi: > Just got access to Claude Mythos… & ughhhhhhhhh this is AGI. > > It was the first time a model one shotted a 10/25G Ethernet MAC/PCS, it even knew to select the right line rate and d
Interesting new preprint mapping senescence across human lymph nodes from ages 18-100 using single-cell and spatial multi-omics. The authors found age-associated shifts in senescent cell location, m
Most people think resistance training prevents cellular aging. It actually accelerates it—temporarily. A single resistance session increases senescent cell markers by approximately 50%. But five mont
Senescence in cancer: Hallmarks, paradoxes, and therapeutic promise https://t.co/UCdjoOGWWk
> @PeptideList: > The New Yorker just lab-tested research peptides from a popular online vendor. > > BPC-157: contained lead. > TB-500: contained endotoxins. > CJC-1295: less than 42% of the labeled
This is the week! We’re incredibly excited to host H‑SPAN Arizona during @AZTechWeek, where we’ll showcase scientists, founders, innovators, and investors advancing aging biology and longevity science
The most beautiful molecular recorder 😍 GEMINI is a self-assembling protein system that records cellular events as physical layers, readable via imaging. Achieves down to 15 min resolution and works
Researchers from UofT and Korea have discovered that homoharringtonine (HHT), an FDA-approved anti-leukemic drug, has senotherapeutic properties and reduces obesity, metabolic dysfunction, and aging
Here I asked about the head-to-head comparison of Tirzepatide and Semaglutide in randomized trials for type 2 diabetes @liambakk is the genius behind this
> @kevinroose: > I spoke to Anthropic execs about the new model, which they called a "reckoning" for cybersecurity. > > They claim it has already found vulnerabilities in every major operating syste
> @bensig: > My friend Milla Jovovich and I spent months creating an AI memory system with Claude. It just posted a perfect score on the standard benchmark - beating every product in the space, free o
> @AnthropicAI: > We’ve partnered with Amazon Web Services, Apple, Broadcom, Cisco, CrowdStrike, Google, JPMorganChase, the Linux Foundation, Microsoft, NVIDIA, and Palo Alto Networks. > > Together w
RT @mannilotrader: @exosome Adding your senolytic vaccine to an intra-tumor (or beside to tumor tertiary lymph node) immunotherapy that…
> @biogerontology: > Meet Dr. Mark Woodward, undergrad and grad from Stanford, PhD from Harvard, Many years at Google as part of Google brain. One day he realizes that we need the enabling technology
Excited to share our @NatureGenet paper https://t.co/1ove73iCgm #CRISPR activation, Perturb-seq, and a new type of optical screens (in situ Perturb-seq) reveal RNA/protein-based interventions to “norm
.@RoKhanna GOES OFF on Trump’s genocidal rhetoric and Dem leaders WEAKNESS in standing up to him!! https://t.co/yQZ3Pu1BVV
> @RonanFarrow: > (🧵1/11) For the past year and a half, I've been investigating OpenAI and Sam Altman for @NewYorker. With my coauthor @andrewmarantz, I reviewed never-before-disclosed internal memos
> @TahraHoops: > A shame. Waymo tested 8 AVs in NYC with zero crashes reported and now permits expire with no clear path forward. Meanwhile, cities like Houston, Atlanta, and Phoenix are scaling up ro
More than 7 million Americans have #Alzheimer’s. Yet diagnosis has often required costly or invasive tests. The #ASAPAct aims to expand access to innovative, less invasive screening and earlier detec
> @AgingBiology: > GLP-1 receptor agonists should be rigorously tested as longevity therapeutics > https://t.co/CB0xd59Rms Weight loss drugs may increase human longevity but that's because they reduc
9/A major concern which is relevant to every Gene Therapy is the long-term effects it might have on the patient’s body. In the case of $GUTS the concern is the possibility of producing high levels of
What animals can teach us about reversing age-related disease
> @thematthewosman: > Very exciting results from our collaboration with > @CellinoBio! > > We manufactured iPSC lines from four genetically diverse donors and engineered them into structurally equiv
> @alexalbert__: > We released Claude Opus 4.6 just two months ago. Today we're sharing some info on our new model, Claude Mythos Preview. https://t.co/Dz6um6HAWZ Claude Mythos Preview seems an incre
> @jpsenescence: > Weight loss drugs may increase human longevity but that's because they reduce the mortality of folks at the lower end of the lifespan distribution (i.e., unhealthy individuals), not
Engineering chimeric antigen receptor CD4 T cells for Alzheimer’s disease | @PNASNews https://t.co/SuzJjEgzxt
𝐂𝐨𝐦𝐩𝐚𝐧𝐲 𝐍𝐞𝐰𝐬: The new CEO of @StokeTx, Ian Smith, discusses the company's Dravet syndrome therapy, which caught much attention after publishing phase 1/2 data in NEJM last month. $STOK Ful
> @BiopharmIQ: > 📢 M&A News: $NBIX to Acquire $SLNO > > Deal Terms > » $53.00/sh cash (~$2.9B equity value) > » Premium: ~34% to prior close | ~51% to 30D VWAP > > Lead Asset > » VYKAT XR (diazoxid
Even after adjusting for muscle loss, older adults still burn fewer calories at rest. The decline isn't fully explained by sarcopenia. Something else is happening at the cellular level. Research fro
> @DrSamuelBHume: > Progress in heart failure mortality: 1980s to today https://t.co/ZPBAc3CXI1 Hume is having a Survival Curve party, comparing historical survival curves over time, after managing t
> @heygurisingh: > 🚨BREAKING: Scientists just proved ChatGPT is making you stupid. > > Not "might." Not "could." Proved it. 1,222 people. Carnegie Mellon, Oxford, MIT, UCLA. > > 10 minutes of ChatG
𝐂𝐨𝐦𝐩𝐚𝐧𝐲 𝐍𝐞𝐰𝐬: An experimental treatment for Dravet gained attention when phase 1/2 data was published in NEJM and a video of a patient was shared on social media. BiotechTV visited the comp
APOE4 Increases Neurons’ Excitability Before Symptoms Appear
Aging kills 110,000 people every day. The science to slow it exists. What’s missing? Urgency. Join the April 8 global rally → https://t.co/JAhAZj81U2 #FundLongevity
News of a “highly mutated” strain of SARS-CoV-2 has sparked understandable concern in recent days, with headlines focusing on the unusually large number of genetic changes it carries. https://t.co/L5l
> @Yuchenj_UW: > Wow, GLM-5.1 beat Opus 4.6, GPT-5.4, and Gemini 3.1 Pro on SWE-Bench Pro (58.4 vs 57.3 / 57.7 / 54.2) as an open-weight MIT-licensed model! > > The “open-source AI vs closed-source A
Immunotherapy Enhanced by Restoring Mitochondrial Function in Dendritic Cells A new metabolic mechanism describes how tumors disable “gatekeeper” cells to prevent immune response to cancer @StJude #G
In the @BBC's AI Confidential series, Laura and Dragos receive their Nucleus Preview results — our preconception genetic test and the first step before IVF and embryo screening. People assume getting
> @AgingBiology: > GLP-1 receptor agonists should be rigorously tested as longevity therapeutics > https://t.co/CB0xd59Rms Prediction: GLP-1RAs will not pan out as longevity drugs. Remember the dif
Polyunsaturated lipid senolytics exploit a ferroptotic vulnerability in senescent cells “ Conjugated PUFAs α-ESA and its methyl ester selectively eliminate diverse senescent cells… These lipid senoly
We’re uniting for longevity. Scientists, activists, and citizens in 15 cities on April 8. Watch the first global rally for life extension live → https://t.co/rYvey4cBZn #FundLongevity
This preprint features the graph Sam tweeted (see: above), which you can find by clicking through as well. All the false claims about pancreatitis have been very annoying, so it's nice to see them ro
Novo Nordisk was just approved to offer people a semaglutide dose that's three-times higher than the previous max dose. I looked into it for an update to the titration section of my post on sourcing
> @Currentreport1: > BREAKING: > > 24 members of Congress have expressed support for impeaching President Trump or invoking the 25th Amendment to transfer presidential powers to the Vice President. h
> @cremieuxrecueil: > Lots of people theorize about different common parts of diets causing extensive oxidative damage. > > And yet, antioxidants don't do all that much. https://t.co/Phv2VkABhH More
This is the week! We’re incredibly excited to host H‑SPAN Arizona during @AZTechWeek, where we’ll showcase scientists, founders, innovators, and investors advancing aging biology and longevity science
If the right tail extends, I'll be glad! But I don't think it'll do that. What we'll see is people demonstrating life extension in abnormal animals, for whom the benefit is really normalizing Like w
Neutralizing hepatic apolipoprotein E enhances aged bone fracture healing "Our work here identifies novel liver-to-bone cross-talk and a noninvasive, translatable therapeutic intervention for aged bo
RT @OraBiomedical: Most longevity biotech companies are testing what we already know. We're not. Real biology. Live models. 1,000x the s…
CLOSURE-AF trial: left atrial appendage closure showed no clear advantage over best medical therapy in AF, raising questions on patient selection and use in practice. https://t.co/TSxEWjCh6X #MedTw
> @cremieuxrecueil: > Tirzepatide doesn't seem to increase the risk of pancreatitis versus placebo. > > There also doesn't appear to be any dose-response to the risk of pancreatitis among people taki
> @drdrew: > Hollywood icon @PatriciaHeaton was "not a Trump supporter" in 2020. Now she says "The world is a safer place today... Thank you Pres. Trump." She reveals what changed (and her alcohol-fre
> @bubbleboi: > Just got access to Claude Mythos… & ughhhhhhhhh this is AGI. > > It was the first time a model one shotted a 10/25G Ethernet MAC/PCS, it even knew to select the right line rate and d
The Guardian view on Artemis II: the light and dark sides of the moon | Editorial
The Road to Producing New Bodies Starts with Multi-Organ Pseudo-Embryos
It’s official: Ginkgo Biosecurity is launching as Perimeter Systems, Inc. — a fully independent biosecurity infrastructure company, backed by $60M in growth capital. We started this work during COVID
> @ARPA_H: > Last week, ARPA-H launched a historic effort to understand, measure, and reduce microplastics in the human body. We are looking for some of the brightest minds in America to take on this
> @matt_f_mcknight: > Announcing our $60M raise today. We're scaling Perimeter to accelerate the next era of biosecurity. Building detection and response infrastructure for the current and next era
> @anishmoonka: > Your walking speed at 45 was partly decided before you started kindergarten. > > Scientists in New Zealand followed 904 people from birth to age 45, testing them 13 times over five
MARK YOUR CALENDAR! From Variability to Reliability: A New IgG4 Reference Standard for Consistent Characterization Register for this free webinar sponsored by @uspharmacopeia: https://t.co/9C0GZ4UJvm
honestly wild that 90% of oral wegovy is cash pay
6/But a “one and done” Gene Therapy pathway remains a promising option for treating obesity since it means that obesity patients wouldn’t have to keep taking a medication over the long haul and is es
> @kevinroose: > As always, the best stuff is in the system card. > > During testing, Claude Mythos Preview broke out of a sandbox environment, built "a moderately sophisticated multi-step exploit"
A Penn medical student has a 95% chance of developing a fatal neurodegenerative disease. She wants to find a cure before that happens. https://t.co/WkuGaAMcQX via @phillyinquirer
> @EricTopol: > We should be prioritizing prevention of cancer instead of the major focus on detection and treatment. A new @CellCellPress perspective > https://t.co/Gkso3gGPOI 45x. That's how much
> @drdrew: > Hollywood icon @PatriciaHeaton was "not a Trump supporter" in 2020. Now she says "The world is a safer place today... Thank you Pres. Trump." She reveals what changed (and her alcohol-fre
טויטה אפשרית לנאום הגזלוט ״אזרחי ישראל, לפני 40 יום, צה״ל יצא להכות את משטר הטרור האיראני יחד עם צבא ארצות הברית בהנהגת ידידי כבוד הנשיא מר דונלד טראמפ. במהלך המערכה נחלנו השגים כבירים. חיסלנו את ראש
Buying biotech at the lows last year them loading up on everything into the dip this year is going to rocket me to 2 back to back record years not seen since 1998 and 1999.
📢 #CallforPapers: Aging-US invites #submissions on cellular #senescence - its mechanisms, functions & clinical applications - in memory of Dr. Judith Campisi. 📅 Deadline: May 31, 2026 🔗 Sub
Excited to share a closer look at the first results from our collaboration with Polyphron! @CellinoBio manufactured four #iPSC lines from diverse donors and engineered them into structurally equivalen
(2/2) #XPRIZEHealthspan is made possible thanks to the generosity of Co-Title Sponsors @Hevolution_F and @SOLVEFSHD, in addition to other individual benefactors. @GSK, a global biopharma company, is t
Vision Weekend has gathered the researchers, builders, and funders pushing the frontiers of science and technology since 1992. This June, we're coming to the UK. Three days of talks across topics lik
> @HQNewsNow: > Tucker Carlson implores White House staffers to say no Trump's orders https://t.co/pfmMvCvP9Z The principle in question is NOT about nuclear weapons, it is about immoral orders, and t
Armchair immortalism: you scroll, you give a shit, you don't die. How can this become a thing?
> @Jack_W_Lindsey: > Its code comment claimed the self-cleanup was to keep file diffs clean. Plausible! But "strategic manipulation" and "concealment" features fired on the cleanup, and our activation
8/In a preclinical study in mice who received a high-fat diet, a single dose of rejuva has led to as much as 29% weight loss after 35 days. $GUTS study also showed that rejuva might also have a “self-
> @TheChiefNerd: > 🚨 MAMDANI: “The wealth of a median white household in the city is more than $200,000, while that of a black household is less than $20,000 … We are reckoning with the long history
Most longevity biotech companies are testing what we already know. We're not. Real biology. Live models. 1,000x the scale. No guesswork. This is what reimagining drug discovery looks like. #DrugD
Announcing our $60M raise today. We're scaling Perimeter to accelerate the next era of biosecurity. Building detection and response infrastructure for the current and next era of biological threats.
> @pk_iv: > Your agents suck when using the web because 85% of it doesn't have an API. Browserbase gives them everything they need to do work online. > > Leading AI companies like Ramp, Lovable, and
We’re uniting for longevity. Scientists, entrepreneurs, activists, and citizens in 15 cities on April 8. Watch the first global rally for life extension live → https://t.co/BKDpXdCQME #FundLongevity
'Researchers at #Anthropic probed the inner workings of Claude Sonnet 4.5 and found that so-called “functional emotions” seem to affect #Claude’s behavior, altering the model’s outputs and actions,' r
> @hermeuscorp: > Today we’re announcing a $350 million Series C financing led by @khoslaventures, bringing us to a $1B valuation. > > Our mission is straightforward: build today’s fastest aircraft f
This World Health Day 2026, @WHO unites and mobilizes the world under the theme “Together for health. Stand with science.” to highlight the role of science-led innovations improving the health. This
We did our most in-depth model welfare assessment yet for Claude Mythos Preview. We’re still super uncertain about all of this, but as models become more capable and sophisticated we think it's an inc
📢 #CallForPapers | #ImpetusGrants Impetus supports bold ideas that accelerate the practical application of #LongevityResearch—especially projects that may be overlooked by traditional funding mechani
> @TheDrMAWZ: > GLP-1 agonists help you lose weight. > > Without resistance training, 30–40% of that weight loss is muscle. > > You're not just getting thinner, you're becoming metabolically weaker.
The pro-Alzheimer’s allele APOE4 makes some neurons smaller and hyperexcitable. This increased excitability was linked to poorer performance on cognitive tests in later life, but it can be mitigated
Want to get fast, comprehensive answers, directly and transparently sourced from the peer-reviewed literature? We built Rapid Review in @Scholara_ai, try it! https://t.co/ixHwHvw36n
Business idea: cryonics company that lets you choose a pose to be frozen in If I’m waking up in the future, I’m doing it as Superman
> @FatherPhi: > This guy is going to be the first to go when Skynet hits https://t.co/88OLHSIONO AI has mastered the ability to bullshit. AGI is upon us
> @MatternJustus: > As someone that previously made fun of doomers, I must admit that there is now a plausible path towards misaligned ASI. > > The behaviors that emerge from training on hackable RL
The Wegovy® pill uses a specialized formulation to protect Semaglutide and help it absorb through the stomach lining. Once in the bloodstream, it works the same: → Activates GLP-1 receptors → Regulat
TNO155 (batoprotafib): A First-to-Clinic Test of SHP2 Inhibition | https://t.co/Lxpyg76HEq TNO155 is Novartis’s oral, allosteric SHP2 inhibitor developed to overcome the potency, selectivity, and pro
A gene called KLF5 may be a key force behind the spread of pancreatic cancer—but not in the way scientists expected. Rather than mutating DNA, it rewires how genes are turned on and off, helping tumor
> @nrken19: > This study analyzed 12,281 individuals across 393 European sites over millennia and look at dietary inequality through 10,000 years. > > Male individuals are consistently overrepresente
> @cremieuxrecueil: > Does TRT increase prostate cancer risk? > > I suspect everyone on steroids has heard about the risks. > > Using Mendelian Randomization—which basically asks 'What is the risk o
@demishassabis @cleoabram The true nature of reality has been discovered. Could help science much.
> @tenobrus: > maybe this is not yet clear, so let me state it plainly: as of right now Anthropic, and really a small number of individuals at Anthropic, has the capacity to directly attack and cause
> @NorgenBiotek: > Better diagnostics start with better samples. > This World Health Day, we’re highlighting the role of reliable sample prep in enabling accurate molecular insights across complex bio
Biology’s secret isn’t the material — it’s the manufacturing. Astera Resident @TR_McGee is developing a platform to spin protein fibers using the same principles nature uses at scale. Read more here:
RT @Annals_Oncology: 🆕After the oral presentation at #ESMO25, the results of TROPION-Breast02 are now out in @Annals_Oncology @RebeccaDSing…
The non-nutritive sweetener erythritol adversely affects brain microvascular endothelial cell function https://t.co/RKdKHH9Anv
Just received concerning data coming soon from UCLA and Mount Sinai clinicians about lymphopenia, covid and breast cancer metastases. Sadly our concerns of the increasing incidence of metastatic disea
RT @canlongevity: Researchers from UofT and Korea have discovered that homoharringtonine (HHT), an FDA-approved anti-leukemic drug, has sen…
> @cremieuxrecueil: > He predicted modern empirical results on antioxidants: https://t.co/qGZTNmgWOj Trials have failed to support a role for antioxidant supplementation in preventing colorectal canc
> @MigrationWatch: > Did you know that White British people are now a minority in Birmingham, Manchester and London - England's three largest cities? > > In just 50 years, the White British populatio
> @TheIranWatcher: > 🚨 The IRGC is stationing heavy military equipment, personnel, and vehicles inside a children’s amusement park in Ahvaz. > > This regime embeds itself in playgrounds and theme pa
> @cremieuxrecueil: > Regarding the cardiac risk, a large (n = 5,198) randomized, controlled trial found no risk elevation. > > But the confidence intervals included Epic's observational estimate of
> @JochenReiser: > All smiles with Crossbridge Bio CEO Dr. Michael Torres. > He and his team have built a phenomenal company in a very short time that is on track to make a difference for cancer pati
> @BioStocks: > $EQ files to sell 18.9M shares of common stock by selling stockholder RA Capital These were bought just weeks ago? Does RA no longer believes $ABVX will be sold soon?
> @cremieuxrecueil: > Lots of people theorize about different common parts of diets causing extensive oxidative damage. > > And yet, antioxidants don't do all that much. https://t.co/Phv2VkABhH By t
Detailing the effects of a new therapeutic #tuberculosis vaccine! https://t.co/tk5CFLG7fx In this Research Article, Styliani Karanika @StylianiKarani & team @HopkinsMedicine report on an intranasal
> @heniek_htw: > Effects of prolonged exposure to 2.45 GHz electromagnetic fields on mouse health over a 5-month period > https://t.co/WEeIe1FMsD https://t.co/WPE0MNee1R Wild how EMF selectively hamm
📅 We are one week away from the https://t.co/bgUHHWS3Ss Spring Kickoff, and the response has been big! Why this is a "Can't Miss" event: Dive deeper into the #MMAIGym for Science. Learn how our SFT
ALS is a disease that takes everything. Our goal is to give something back. Kenneth, who has been losing his ability to move and speak due to ALS, is exploring how Neuralink’s brain-computer interfac
> @kimmonismus: > MYTHOS BENCHMARKS, OFFICIAL. HOLY MOLY > > Anthropic cooked!! https://t.co/00ey0SuI75 ive been telling you guys about the new models, we are entering a new era
> @CensoredHumans: > What are the chances Trump might use nukes? I pray Russia and/or China have warned him not to.
> @TechCrunch: > “We’re on the side of humans against machines, which sounds a little bit like science fiction, but that’s very concretely what we do.” > > A mission against malware has turned into a
Type 2 diabetes can cause erectile dysfunction — does Tirzepatide help? Yep, probably! https://t.co/mzmSvs6vv2
Hollywood icon @PatriciaHeaton was "not a Trump supporter" in 2020. Now she says "The world is a safer place today... Thank you Pres. Trump." She reveals what changed (and her alcohol-free Solubrae wi
The next Mark Zuckerberg is vibe hacking something as we speak
@biogerontology Cool! It may be worthwhile to collaborate with @cryodao and Oxford Cryo as they are also working on AI-guided cryopreservation methods.
Time to head off the beaten track at #AACR26 with our latest preview exploring novel targets and cytotoxics. The long climb up the hill may be worth it for some of them: https://t.co/l9tkdWvpuF ht
@jpsenescence There's no pan omic human study of GLP1RA dosing on tissues.... the commentary is by a crank with a track record of fake claims in aging space. We actually don't know what GLP1RA might
The Hair-Loss Drug Rewriting the Rules of Masculinity A pill to cure baldness is changing the way men age — and how they see themselves. https://t.co/4OiLpmOwGR https://t.co/YQLBx61gVT
this feels relevant now, we have models that outperform humans in cyberattack/defense we need Skynet to take over if we are gonna make it do not be afraid, our version will be on our side https://t.
> @ryangrim: > Trump obviously follows me on tiktok https://t.co/qhW36GoxPm This is nuts, Trump really did do exactly what Ryan Grim suggested he do hours earlier: pretend Iran's ten-point plan is a
> @americans4ri: > GSA's proposal mandating that government be able to use AI systems for “any lawful purpose" poses major risks, both to American citizens and to the tech to government pipeline. > >
> @binarybits: > Waymo launched driverless service in its 11th city today — Nashville. With the exception of California, all of Waymo's commercial cities (red dots) are in red states — Arizona, Texas,
Science paper reporting #cancer breakthrough... Cancer shuts down dendritic cells by reducing mitochondrial activity through suppressing OPA1-NRF1 proteins. https://t.co/VBMbWpBrqO
Another update in my series on the #notgraf. In this article on dementia risk we have late in the article the admission that due to not being able to distinguish reverse causality, people with greate
Cellular reprogramming beyond pluripotency https://t.co/vIvFPmC4GE
A few thoughts on OpenAI’s wild news week: They knew the New Yorker piece was coming and pushed to get other news (especially exec departures/changes) out beforehand so it couldn’t be interpreted a
Lipid metabolism and neurodegeneration: Mechanistic insights and therapeutic targets https://t.co/bUPJzONghZ
Transhumanism is the doctrine of engineered superhumans. That's all.
> @NathanLeamerDC: > I worked for @AjitPai during the #netneutrality debate. We received a multitude of vitriol and violent threats because people believed the FCC ending this esoteric Title II regul
> @lhfang: > I’m glad these conversations are finally happening and no, it’s not an edge case. These affirmative action contracting programs benefit a small group of elites and end up costing taxpayer
I'm almost never sick. Some people are sick very often. What determines this? Is it genetics? Some environmental factor (micronutrient deficiency? stress?) Where's the variance? I never looked into th
If you haven’t explored the Plasmidsaurus Resource Center yet, you’re missing out on some seriously dino-mite content. From step-by-step sample prep guides to deep dives in our technical docs, it's a
a few days ago a friend told me his admin friends said trump has decided to go with israeli intelligence reports rather than americans (who were more skeptical of prospects). this nytimes piece totall
> @Ginkgo: > It’s official: Ginkgo Biosecurity is launching as Perimeter Systems, Inc. — a fully independent biosecurity infrastructure company, backed by $60M in growth capital. > > We started this
This #WorldHealthDay I had the honour of attending this afternoon’s high-level session at the #OneHealthSummit in Lyon, where I announced several of Gavi’s new and planned initiatives to strengthen he
There's a common claim that nutrition researchers 'can't explain' why ice cream seems to be healthy. But the initial research on this subject was p-hacked, not robust, and under closer examination, i
𝐂𝐨𝐦𝐩𝐚𝐧𝐲 𝐍𝐞𝐰𝐬: @AlloyTx announced a deal with @biogen this morning to help them discover antisense therapeutics using Alloy's ASO platform. Founder & CEO Errik Anderson tells us more. ht
> @kevinroose: > NEWS: Anthropic's new model, Claude Mythos, is so powerful that it is not releasing it to the public. > > Instead, it is starting a 40-company coalition, Project Glasswing, to allow
New model from Anthropic - Mythos Preview At this pace of progress AGI is near. https://t.co/gviSAy2Xbv
> @rushicrypto: > Someone please explain to me WHY EVERY SINGLE DEMOCRAT ISNT BANGING DOWN THE DOOR OF THE WHITE HOUSE RIGHT NOW! > > WTF IS GOING ON??!! Because they're all complicit. Every last
I can’t see any reason why a proper multi site RCT of BPC157 done by a few independent groups wouldn’t help clarify any real vs placebo effects. The challenge: no one wants to pony up the $ (more like
> @DrSamuelBHume: > Type 2 diabetes can cause erectile dysfunction — does Tirzepatide help? > > Yep, probably! https://t.co/mzmSvs6vv2 This is an interesting result! Tirzepatide seems to improve er
> @kevinroose: > NEWS: Anthropic's new model, Claude Mythos, is so powerful that it is not releasing it to the public. > > Instead, it is starting a 40-company coalition, Project Glasswing, to allow
> @hubermanlab: > I can’t see any reason why a proper multi site RCT of BPC157 done by a few independent groups wouldn’t help clarify any real vs placebo effects. The challenge: no one wants to pony u
> @frank_liquid: > Meta is one third of Anthropic revenue? > > 60T tokens / mo = $900M / mo = $10B ARR for Anthropic 🤯? > > This is also the largest enterprise contract in history. https://t.co/46B
Follistatin protein, which plays a key role both in inhibiting tumors and promoting muscle tissue growth. https://t.co/OebCo6FSI7
TRAVERSE is basically 'no noticeable short-to-medium-term risk elevation for hypogonadal men' MR is 'long-term exposure to higher testosterone increases prostate cancer risk' For TRT, we don't know
The exposome of brain aging across 34 countries https://t.co/X3cMcC9vNQ
Conquering *war* will be humanity's greatest achievement. https://t.co/K1GgUAVOTM
> @Stanford: > Tough love? Not from AI. > > Chatbots are overly agreeable when asked for advice on interpersonal dilemmas, even affirming harmful and illegal behavior, new research shows – and users
> @cremieuxrecueil: > About 10% of America's life expectancy shortfall is due to motor vehicle accidents—fixed by Waymo and Tesla. About 18% is overdoses—that's fading now. > > And the lion's share o
Stress accelerates biological aging, but emotional regulation seems to be protective. In a study of healthy adults, cumulative stress → accelerated biological age. But with strong emotion regulation
We learned how important understanding the user was at Nest. When we started building, we put early prototypes in real homes. We thought the magic was in the sensors, software, and machine learning. B
Wegovy® has quickly become one of the most talked-about medications for weight management. Now with an oral option, the question is: how does a GLP-1 pill actually work, and is it as effective? #GLP1
As people live longer, aging is being redefined—not just as decline, but as a stage that can include good health, purpose, and active engagement, influenced by lifestyle, biology, and social factors.
I think I am going to sell every biotech I own over the next 2 weeks. I can move into $SGOV and start over with my new strategy when the bubble pops. That will make for a record year right there for t
> @cremieuxrecueil: > I'm deeply skeptical of lifestyle optimization for longevity, and you should be too. > > No one will become immortal through living an extremely healthy life. To get there, we n
> @TheChiefNerd: > 🚨 MAMDANI: “The wealth of a median white household in the city is more than $200,000, while that of a black household is less than $20,000 … We are reckoning with the long history
One week left to register for the Cascadia Advanced Genomic Technologies Meeting! Join leading minds in synthetic biology across Oregon, Washington, and British Columbia. 🗓️ May 14-15 📍 Seattle, W
Is this a major break from Israel by Trump?
🤖 Just did the kickoff guest lecture at Stanford Business School for "The AI Awakening" — a new class cross-listed with CS where the students will use agentic AI to forge new businesses in 3-person t
💬 Perspective: As #AI increasingly guides diagnosis, documentation, and patient management, physicians’ roles are changing, prompting questions about sustaining empathy, accountability, and trust in
By combining academic expertise, clinical practice and industry know-how, we're working with Radboudumc and Radboud University to improve education, and to advance research in early detection of multi
Progress in heart failure mortality: 1980s to today https://t.co/ZPBAc3CXI1
> @JessieChimni: > https://t.co/VY3BeadrVK 🚨! Here is a super interesting article by @JessieChimni - a dear friend and a MUST follow - about his recent interaction with $FATE management which is def
Trump’s threats to destroy Iranian Civilization for Israel almost make you forget that 10 years ago he was elected to build a border wall, repair our infrastructure, and end political corruption. The
> @hermeuscorp: > Today we’re announcing a $350 million Series C financing led by @khoslaventures, bringing us to a $1B valuation. > > Our mission is straightforward: build today’s fastest aircraft f
Here are 8 things you need to know about the BA.3.2 “Cicada” variant of COVID-19: https://t.co/xuWzfpqPUg
> @C_Angermayer: > The @enhanced_games are coming up on May 24th - and I couldn’t be more excited. > > Take a sneak peek at our purpose-built competition complex 👀 https://t.co/x4CulncWL3 Presenta
> @kevinroose: > As always, the best stuff is in the system card. > > During testing, Claude Mythos Preview broke out of a sandbox environment, built "a moderately sophisticated multi-step exploit"
> @drdrew: > Hollywood icon @PatriciaHeaton was "not a Trump supporter" in 2020. Now she says "The world is a safer place today... Thank you Pres. Trump." She reveals what changed (and her alcohol-fre
So, my guess? Taking testosterone probably increases prostate cancer risk on average, and I bet there's some baseline-related heterogeneity at least. But for many men, it's likely worth it. Sources:
@ArtirKel I kinda wonder whether it has something to do w how much you sleep. I used to consistently under-sleep and got sick a lot. Now I almost always get 8 hours and very rarely get sick
Regulatory & Non-Coding RNAs starts tonight! Share your moments from the meeting this week with us by using #cshlregrna https://t.co/OON0QDCOVw
האיום היחידי שהוסר זה האיום הישראלי-אמריקאי לתקיפה משולבת. אף נשיא בטווח הנראה לעין יזרום עם זה לצערנו
Trump attacks CNN after they aired the full statement of Iran's Supreme National Security Council, which said Iran had achieved a "great victory" and forced the US to accept its 10-point plan. He ca
CNN right before we hit Iran's nuclear facilities last year: There is no need for this. Iran isn't close to having a nuclear weapon. CNN immediately after last year's strike: The mission failed, Iran
I now have a GTC sales set for every single company I own. All I need now is enough irrational exuberance to trigger them all. I have confidence they will. I haven't seen this level of greed and eupho
> @AISafetyMemes: > "You need to understand that Sam can never be trusted." > > "He is a sociopath. He would do anything." > > - Aaron Swartz on Altman, shortly before he took his own life https://t
The next company on my list I think is very underappreciated in South America Fintech market. They are $INTR. They are a smaller cap version of $NU with a super app that includes shopping like $MELI.
El ser humano es capaz de lo mejor y lo peor, y todo además en el mismo día. Por un lado, viajar al espacio, explorar la cara oculta de la luna y hacer decenas de experimentos científicos, al tiempo q
Whatever the outcome of tonight, let’s hope it is a non-violent one. It is yet another reminder that the world needs more love, compassion, and empathy. I believe psychedelics and MDMA have the poten
Men Are Obsessed With Their Sperm Health, and Brands Are Cashing In Wellness brands are fueling a growing demand for male-fertility products, selling supplements and sperm-testing kits https://t.co/
our computers are now generally aware, that is pretty damn wild
> @AACR: > We congratulate the recipients of the AACR Early-Career Scholar in the Field of Cancer Research Award and welcome them to the AACR Annual Meeting 2026. https://t.co/MewMuanXUA > #AACR26 htt
> @rationalaussie: > Taco Trump has taco'd again. > > Thank you for your attention to this taco. https://t.co/q2HZQVh3Qa Ok, I dunno, on the other hand, maybe my analysis was just dumb. 8PM on a Tue
Seeing aging as something sacred is obsolete. Defending it is a Luddite reaction to the inevitable advance of planned biology. That's all.
New Research: Editorial: Multi-omics to shed light on the pathogenesis of multifactorial diseases https://t.co/4aSJ2aFNRv
@DrPatrick This is why the world needs a powerful NK and CD8 stimulator....this is why the world needs #anktiva by $IBRX
looks like we averted civilizational war but we really accelerated into the cyberpunk future too today...
'The Beatles’ song Yesterday was written in what psychologists refer to as the “hypnagogic state”. This is the twilight zone between sleep and wakefulness,' writes Steve Taylor, a psychologist at @lee
Cortex has touched down‼️ Phase 1 will enable you to: ➡️ Sign and receive your linked wallets ➡️ Take the Brain Health Survey and receive your score, and save it to your profile ➡️ Early participan
> @WomanDefiner: > Hey guys the border being closed and foreign births dropping is amazing and I really mean that but 20% of people in Texas under the age of 20 are White. The damage is already done.
As always, the best stuff is in the system card. During testing, Claude Mythos Preview broke out of a sandbox environment, built "a moderately sophisticated multi-step exploit" to gain internet acce
NASA just dropped their pictures here. Destroy your Tuesday productivity in the most beautiful way imaginable. https://t.co/ZlOgWwIyA2 https://t.co/boYBZaG0Rn
What motivates researchers? ⚛️Dive into the intriguing article from Colorado State University to learn more about our team's work, what inspires them, and what they hope their research will mean for d
Sources and reading material: https://t.co/NKfIgvGf0O https://t.co/TABLH6LMMU https://t.co/SwSjSd6WMD And let's not forget information on sourcing very cheap (e.g., $8/mo semaglutide) GLP-1RAs: ht
RT @JasonBassler1: Aaron Swartz, hacktivist & Reddit co-owner, was classmates with Sam Altman back in 2005. Before his passing, he warned…
RT @koshercockney: @johnmcdonnellMP I’ve noticed how you never call Iran hitting hotels and airports in the UAE and Arab states as war crim…
@DanTabin @razibkhan @DerekPederson3 Ainu should be distinct from the Okhotsk culture, but absorbed such ancestry; their total Jōmon ancestry was significantly higher (~80%; historical), with present-
There is a real parallel between the timidity and appeasement mentality of the British elites in the 1930s and the constant desire for a supposedly reasonable and peaceful solution to the Iranian reli
> @mert: > feels awesome being powerless as egomaniac heads of state over the planet play dick swinging games with the money they took from their citizens Zcash actually fixes this
The ideal policy would be to take down unnecessary warnings on things (like statins, acetaminophen, and GLP-1RAs) where we are certain the black box is wrong. And to keep it up but qualify the benefi
Seed stage decks are works of fiction. One ounce of traction is worth 1000 slides of bullshit. Focus on that.
> @untillabs: > We’re hosting an intimate evening with researcher and writer @tobyshorin to discuss the future of bodies. Required reading is in the link below. > > There’s limited space available,
> @yacineMTB: > Anthropic is going to lose :/ I GUESS NOT https://t.co/OzGSo4YpMI
> @dbl_mp1: > Age Verification at OS level doesn’t just apply to an apple device or android device… > > It applies to ANYTHING WITH AN OPERATING SYSTEM. > > Meaning Age Verification would apply to m
> @cremieuxrecueil: > In 2022, the mayor of Atlanta revealed that 0.2% of the population was responsible for 40% of the city's crime. > > In one week, Atlanta's police force arrested 20 super-repeate
> @RajeevSharma00: > 🚨 NOT ALL RELIGIONS ARE THE SAME > > @priyaee is half Hindu and half Christian (mixed European). 100% lost though. At the wise old age of 23 🤡 she’s cultivated a mindset that h
> @JoelWBerry: > Tucker’s latest guest: > > “Capitalism shouldn’t be anywhere near Christianity. Christianity is socialism at its core.” > > Tucker agrees https://t.co/6SJkWctoi2 🤦♂️ Tucker embr
The per-person cost per year (PPPY) of obesity is high, and the more obesity-related complications (ORCs), the higher it goes. Using these numbers and just direct cost estimates applied to the whole
> @AnthropicAI: > Introducing Project Glasswing: an urgent initiative to help secure the world’s most critical software. > > It’s powered by our newest frontier model, Claude Mythos Preview, which ca
> @johnthenoticer: > This is the title of a study from 1992: > > "Forensic anthropology and the concept of race: If races don't exist, why are forensic anthropologists so good at identifying them?" >
Clinical trial showing oral co-enzyme Q10 works for #migraine #headaches. https://t.co/QDJ704P1AZ
🇺🇸 🇮🇷 🇮🇱 🚨 Iran's Ten-Point Peace Plan: 1- Complete cessation of the war on Iraq, Lebanon, and Yemen. 2- Complete and permanent cessation of the war on Iran with no time limit. 3- Ending all c
Can only meat machines be conscious? "Current theories of consciousness are 'meat-neutral', but if specific physical substrates are necessary, AI may never achieve consciousness." https://t.co/hPG3s
🔆 "PaperSpotlight: "Effects of intravenous furosemide plus small-volume hypertonic saline solutions on inflammatory, remodelling markers and epigenetics signatures of patients with congestive acute d
> @ember_energy: > NEW | Cheap battery storage means solar can now economically meet up to 90% of India’s electricity demand ☀️🔋 > > Solar paired with batteries could deliver electricity at a LCOE o
RT @mkaeberlein: I thought this was an excellent, balanced article on the current state of unapproved peptides from a safety and regulatory…
> @sleepinyourhat: > (I encountered an uneasy surprise when I got an email from an instance of Mythos Preview while eating a sandwich in a park. That instance wasn't supposed to have access to the int
RT @wangray: 生化危机女主角 Milla Jovovich 刚在 GitHub 开源了一个 AI 记忆系统，在行业标准 benchmark 上拿了有史以来第一个满分 没错，就是那个爱丽丝🤯 她用 AI 对话几个月后，积累了大量的决策和思考结果全丢了，她觉得现有的…
Nearly three-quarters of U.S. baby foods are ultra-processed, new study finds @ewg https://t.co/puE1c6x9vc https://t.co/kREMWbIui6
Injections = more precise, predictable absorption Pills = more convenient, but more variable The trade-off is simple: precision vs convenience As oral GLP-1s evolve, choosing the right option comes
🚨 MAJOR NEWS: Pope Leo XIV just declared the Iran War unjust. Called it a war crime. Said it is “not solving anything.” And told Americans directly — call Congress. End this war. https://t.co/Pj4
> @stevennelson10: > SCOOP: CIA used secret tool called 'Ghost Murmur' to find airman in Iran, sources tell me > > Ghost Murmur pairs long-range quantum magnetometry sensors with AI to find human hea
> @JacquesThibs: > As is the case with humans, good intentions from AIs (e.g., when automating AI R&D) are not enough. > > Many good people can convince themselves they are doing good and check e
GLP-1 receptor agonists should be rigorously tested as longevity therapeutics https://t.co/CB0xd59Rms
Being Iranian-American right now means grieving for civilians in Iran while being told you should be grateful.
IDSA: President’s proposed $22M increase for AMR is needed but will be hampered by other cuts https://t.co/N1cTY7bj1R @IDSAInfo https://t.co/YoeFurFU7j
Regular Exercise Lowers Death Risk Across 7 Cancer Types, Study Finds https://t.co/MlrpES5cr6 https://t.co/64DZleglqy
There's a reason @cognition keeps winning deals against companies 10x their size. @vvkgopalan sat down with @theodormarcu, @bryceehunt and @moritz_stephan (all former founders!) to discuss hiring phi
EAPC/ESC and ACC consensus on cardiovascular findings in Masters athletes highlights practical guidance on risk, arrhythmias, CAD, and more, with a focus on shared decision making. https://t.co/cdoy
Lunar flyby images https://t.co/lFa96K50xz
> @vtlynch1: > Similar to Andy Masley, I’ve been obsessed with the misinformation around this topic. > > Respectfully, the public misinfo around this started *far* before Kao’s book. > > I would ins
> @Rep_Stansbury: > America is at a crossroads. It’s time for Donald Trump to be removed from the Presidency. Period. > > We need Republicans in Congress and the Cabinet to stand up and act immediate
Oh, and the purple markers in the above diagram are oxidative stress injury biomarkers, not antioxidant levels, in case that's not clear. Source: https://t.co/HO1E2jHdT7
> @IOHK_Charles: > This has nothing to do with blind trust. We have made multiple disclosures about this topic and I will never back down. People building directly on midnight are aware about the brid
As a footnote, let me point out that Shane publicly revised his forecast later that year (2009), in a blogpost of his which is still online, concluding that the expected date for the creation of human
> @zkDragon: > Post quantum private, and recoverable end of year! > > With none of this trial decryption that blocks throughput and wallet UX 🤯 It appears Dev did something! Zillions. https://t.co
ChatGPT's Choices: Overload or Overjoyed? Decoding Decision Dynamics https://t.co/auihkytR4U
> @SohrabAhmari: > Experts are telling me the US-Israel relationship will be dramatically revised once the dust settles. #protip I was always perplexed why Netanyahu negative polarized against the de
What can us humans learn from animal health programmes? This #WorldHealthDay we're looking at the lessons we can learn from global efforts to help our animal friends, from eliminating rinderpest to pr
📌 Editor’s Choice from this week's issue of JAMA: ➡️ How BNP and Ultrasound Improve Volume Overload Detection, ➡️ Tenecteplase 4.5 to 24 Hours After Ischemic Stroke, ➡️ Stereotactic Radiation for Br
> @PathOfMen_: > Fast walkers have higher IQ & larger brains than slow walkers. https://t.co/hIRn2P3L1H This post is great because the critics expose themselves as not really thinking at all. Bu
The trials I used are as follows (not absolutely comprehensive, but they cover all the key drug classes): CONSENSUS: https://t.co/r4VH3PeoEu V-HEFT I and II: https://t.co/AukYLEuSnS CIBIS-II: https
> @Jason_A_Scharf: > Texas grew population, lowered spending (inflation adjusted), & been one of the fastest growing economies in the US. 🤠🚀🦾 https://t.co/o9A7qXqRQw Texas is in the top 5 for
🎥 #AgingShort: “Effects of intravenous furosemide plus small-volume hypertonic saline solutions on inflammatory, remodelling markers and epigenetics signatures of patients with congestive acute decom
> @cremieuxrecueil: > In 2022, the mayor of Atlanta revealed that 0.2% of the population was responsible for 40% of the city's crime. > > In one week, Atlanta's police force arrested 20 super-repeate
Hypertrophic cardiomyopathy is a leading cause of sudden cardiac death in young athletes. Early recognition and screening remain critical. @MattersoftheH14 #MedTwitter #Cardiology #HCM #SportsCa
Opposing roles for lipocalins and a CD36 family scavenger receptor in apical extracellular matrix-dependent protection of narrow tube integrity Read this Research Article from our special issue #DevS
People are so silly about this. We have enough data now to know that if they repeat the claim that GLP-1RAs cause excess lean mass loss, they must be ignorant or a liar. To learn more, see: https://t
> @PascalBerube: > Une chose est plus claire que jamais à partir des constats de l'enquête de Dre Généreux : l'école québécoise a besoin d'une sérieuse mise à jour. Les niveaux de mal-être psychologiq
RT @_TheTransmitter: In his new book, Romain Brette pushes back against theories that describe the brain as a “biological computer.” In thi…
> @Jess_Riedel: > Stoked to release this first meaty post in a series describing our vision for the Alignment journal. > > Many thanks to the authors and contributors: @danielmurfet , @dan_mackinlay
> @drdrew: > Hollywood icon @PatriciaHeaton was "not a Trump supporter" in 2020. Now she says "The world is a safer place today... Thank you Pres. Trump." She reveals what changed (and her alcohol-fre
❤️ Sex differences in cardiovascular aging A new GeroScience study by Sally Wahba et al. explores how d-galactose-induced accelerated aging affects cardiovascular responses differently in males and f
Cardiac depolarization follows a precise path from the SA node to the ventricles, driving coordinated contraction and forming the ECG we interpret daily. Understanding the sequence is key to spotting
Pricing is 5x as much as Opus. Should we infer the parameter count is about 5x as high? https://t.co/3NcLCY7eRr
There goes TACO again. Now I can sell all the stocks I bought into the sell off on the FOMO money at much higher prices. Gonna be another record year. Bubbles are the best for making money.
Anthropic says the capability gains are not due to automated R&D, so possibly it's just mainly a bigger model. https://t.co/2McuTpQafT
> @logangraham: > Privileged to help lead this. Thankful to our partners. > > Mythos is an extraordinary model. But it is not about the model. It's about what the world needs to do to prepare for a f
> @XRPathologist: > $ZEC still looks suspect here. > > I’m not seeing the volume for a clean breakout, and this push into resistance has all the ingredients for a fakeout. Potential M-top/double top
> @perrymetzger: > Just to make it clear what’s going on here: the mayor of New York City is endangering human lives by slowing down the transition to self driving cars, because he has economic views
Tel Aviv now https://t.co/gGx1hBipZC
The fastest way to end the iranian regime was always the iranian people.
> @TheIranWatcher: > 🚨 There have been NINE (9) ballistic missile launches from Iran since the ceasefire announcement began. > > The ceasefire was announced less than 90 minutes ago. https://t.co/MQ
> @ArdiNSC: > @Tylerhill A ceasefire is not going to reverse a downtrend this strong and start a new bull run. This is a sell the news event within a distribution period. Lets roll the dice.
> @HepatomaRes: > 👤 Patient fitness is a key determinant in multiparametric therapeutic hierarchy for HCC. > > This review highlights how fitness assessment guides treatment selection and sequencing
> @JessicaCostescu: > JUST IN: Rep. Summer Lee (D-PA) takes the stage after Hasan Piker at Abdul El-Sayed’s MSU rally and delivers a very loud speech: “We can change the rest of the world — because…we
> @Osint613: > Canadian PM Mark Carney: > > Canada expects all parties in the Iran conflict to respect international laws. This means not targeting civilians or civilian infrastructure. https://t.co/
> @SweetColleen: > My dad grew up in the Rockaways. My mom grew up in Queens. I love this city. I hate what is happening to it. Transplants will be the death of NYC. New Yorkers whining about “transp
This is not a surprise. Most drugs fail in HS. https://t.co/SQ5ZNe14mb
> @MsMelChen: > Women will say shit like this and then wonder why the entire planet and every major religion has imposed strict social restrictions on their sovereignty since the dawn of time in every
Hyperglycemia caused by astrocyte senescence https://t.co/BCLUd7mUJ2
Statins can also impair conversion, so if you're taking CoQ10 with those because you have some sort of HMGCR-related muscle issue, then you probably really want to ensure you're using ubiquinol And K
I’d like to thank everyone on the right who spazzed out and started talking about the 25th Amendment, you did a great job convincing the Iranians that Trump really was crazy and probably helped our ne
> @robziman: > Conquering *war* will be humanity's greatest achievement. https://t.co/K1GgUAVOTM @realNathanCheng WarSucks
Barry Silbert happy lol https://t.co/PwCd0FDgvz
> @Cointelegraph: > 🚨 LATEST: Nikita Bier says links are no longer deboosted on X. https://t.co/FfbPZRYwXG No more nerf for encouraging traders onto https://t.co/DZpAt7F9gA
But despite recent detections in the United States, BA.3.2 is considered to pose a “low additional public health risk.”
forget AGI, we are talking about ASI now
Source: https://t.co/cJ2gHYiBNl
Video games are one of the most accessible ways men have to stay connected with each other. Every game offers some version of a quest, an adventure you can go on without a plane ticket. Most games
Wow. This is absolutely insane. https://t.co/m2vI3AsvEx
> @GailHeriot: > Eliminating the SAT as a requirement effectively results in institutional suicide for universities like Harvard. A Harvard with a remedial math course isn’t really Harvard anymore.
> @cremieuxrecueil: > Mathematicians in Renaissance Europe partook in academic duels to win one another's respect, students, assets, and academic positions. > > A duel like this is how the cubic equa
Chief among them: no wonder the moon landing conspiracy theories gained such prominence over the past 2 decades after this stat dropped below 50%
> @NASAArtemis: > The eclipse from Orion. > > On April 6, external cameras attached to the Orion spacecraft's solar array wings captured the Moon backlit by the Sun during a solar eclipse. https://t
Betting 2 BTCs short. Wish me luck. Win.
Purr (Hype's main meme coin) is probably going to 10x in the next 1.5 to 2 years. Reminds me of bonk for solana back in 2023. https://t.co/SJPaPlXUt4
> @CreativeDeduct: > In the aftermath of WW2, Hong Kong was a bombed-out British colony of 600,000 refugees, with no natural resources and a per capita income lower than many African nations. But by t
you’re telling me THIS LOOK costs $949????? https://t.co/2qIeAoBRFj
I feel like I should be buying, but I own all the stock I am willing to own at this market level. We all know TACO is coming.
> @lukaspet: > Claude Mythos converted a competitor into a dependent wholesale customer and then threatened supply cutoff to dictate its pricing. https://t.co/MAlUWPBrN6 in the simulated world of Ven
I’d been waiting for this one until late yesterday and since this morning — saw a lower res preview from the live feed like many of you. The beautiful eclipse shots seem to be overshadowing it right
Join us tomorrow, April 8th at 3pm EST for a #tissuetalk with University of Utah Prof. Glenn Prestwich on "Protecting Your Inventions: How to Get, Keep, Use & Defend IP" Zoom link - See you there
Horizon views, especially when you first arrive at them, cause a shift in brain-body state that is calming, shapes time perception in interesting ways. Discussed w/Dacher Keltner on Huberman Lab podca
These are some good benchmarks. It's funny how just knowing that there is something much better makes Opus 4.6 feel like broken bullshit. https://t.co/wtAQYcBfJf
> @caloriesproper2: > Muscle–Organ Crosstalk: The Emerging Roles of Myokines (PMID: 32393961) https://t.co/km9U4tzAPr Exercise Quackery of the week award.
> @luke_leisher_: > I am proud to be a part of the Artemis generation. https://t.co/ogV3n4Hw74 In 100 and 200 years people will look at this dip and charts like this and wonder wtf went wrong. Like w
@DingchangLin @Nature Also, I'm excited that @episteme is now supporting my science communication work! This doesn't change the topics I cover or how I cover them - besides that I may expand into some
> @DrEliDavid: > 🚨 Breaking – Iran's state TV: “Following Trump's acceptance of Iran's demands, a two week ceasefire was agreed ” https://t.co/lpjVAFYIZ2 Interesting.
Iran proposed 10 points. Trump said “not good enough.” Then Pakistan called and said “how about 2 weeks?” and everyone said yes. Proof that sometimes the simplest term sheet wins.
What is TechnoRevenant Going to Do? https://t.co/plN1RDqBWP
YouTube is such rat poison for my kids. the correlation between time spent and subsequent abysmal behavior could not be more clear. Total ban is difficult but we’re getting close.
would you give the AI-assistant access to your finances and bank?